Evidence map›Paper›PMID 31226950›Full record

SynthesisBMC infectious diseases2019

The pharyngeal carriage of Haemophilus influenzae among healthy population in China: a systematic review and meta-analysis.

Peng Yang, Jieming Zhang, Anlin Peng

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Oropharyngeal Carriage ofPathogens (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Peng YangShantou University Medical College, 22 Xinling Road, Shantou, 515041, China.
Jieming ZhangWuhan University School of Health Sciences, 115 Donghu Road, Wuhan, 430071, China.
Anlin PengWuhan Third Hospital-Tongren Hospital of Wuhan University, 241 Pengliuyang Road, Wuhan, 430061, China. 13531154018@163.com.ORCID http://orcid.org/0000-0001-7601-8993

Funding

Health Commission of Wuhan Municipality WX17A04
6 · The paper itself

Abstract

backgroundA nationwide investigation on the carriage proportion of H. influenzae among healthy populations is lacking in China. The purpose of the study was to review the prevalence of pharyngeal carriage of H. influenzae among healthy populations in China, and explore its influencing factors. The serotypes distribution of H. influenzae was also analyzed.

methodsA systematic search was conducted with key words "Haemophilus influenzae", "Carriage", and "China" or "Chinese" from inception to March 2018. After careful screening, the data of included articles were extracted with a pre-designed excel form. Then, the pooled carriage proportion of H. influenzae was calculated using the random effect model.

resultsA total of 42 studies with 17,388 participants were included. The overall pooled carriage proportion of H. influenzae was 0.17 (95% CI: 0.13-0.21), and the carriage proportion largely varied by province. Subgroup analysis indicated that the pooled carriage proportion was 0.17 (0.13-0.21) for children, and 0.14 (0.7-0.23) for adults. There were no statistically significant heterogeneity between subgroups by age (p = 0.65), sex (p = 0.88), and season (p = 0.10). The pooled carriage proportion of Hib was 0.01 (0-0.02), while the carriage proportion of NTHi was 0.22 (0.13-0.31).

conclusionIn China, the carriage proportion of H. influenzae among healthy population was low, but it largely varied by provinces.

Indexed as

AdolescentAdultAgedAged, 80 and overAsymptomatic InfectionsCarrier StateChildChild, PreschoolChinaFemaleHaemophilus InfectionsHaemophilus influenzaeHealthy VolunteersHumansInfantInfant, NewbornCarriageHaemophilus influenzaeHealthy populationMeta-analysis

Identifiers

PMID31226950
PMCPMC6588945

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.