Evidence map›Paper›PMID 31226874›Full record

ArticleInternational journal of environmental research and public health2019

Association between Potentially Inappropriate Medication Use and Chronic Diseases in the Elderly.

Tzu-Chueh Wang, Pou-Jen Ku, Hai-Lin Lu, Kung-Chuan Hsu, Damien Trezise, Hue-Yu Wang

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Observational
  6. Article
  7. Sex-specific medication trajectories in older adults newly diagnosed with diabetes.Exploratory research in clinical and social pharmacy · 2023
    Article
  8. Article
  9. Potentially Inappropriate Medication Use in Patients with Dementia.International journal of environmental research and public health · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Potentially Inappropriate Medication among Older Patients Who Are Frequent Users of Outpatient Services.International journal of environmental research and public health · 2021
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tzu-Chueh WangDepartment of Pharmacy, Chia Nan University of Pharmacy and Science, Tainan City 71710, Taiwan. tzchwa@mail.cnu.edu.tw.
Pou-Jen KuTaiwan Pharmacist Association, Taipei City 10452, Taiwan. kupoujen@yahoo.com.tw.
Hai-Lin LuDepartment of Information Management, Chia Nan University of Pharmacy and Science, Tainan City 71710, Taiwan. hllu2719@gmail.com.
Kung-Chuan HsuGiraffe Pharmacy, Tainan City 71049, Taiwan. gighv206@gmail.com.
Damien TreziseDepartment of Applied Foreign Languages, Chia Nan University of Pharmacy and Science, Tainan City 71710, Taiwan. damien@mail.cnu.edu.tw.
Hue-Yu WangDepartment of Pharmacy, Chia Nan University of Pharmacy and Science, Tainan City 71710, Taiwan. tzchwa@mail.cnu.edu.tw.
Chia Nan University of Pharmacy and Science · TWChi Mei Medical Center · TWTaiwan Nurses Association · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-term continuous exposure to potentially inappropriate medications (PIMs) can lead to adverse events in the elderly. However, the effects of long-term exposure of the elderly to PIM and the relationship between PIM and chronic diseases remain unclear. The objective of this study was to investigate the continuous use of PIMs in a community-dwelling elderly population. A cross-sectional population-based study was conducted using community pharmacy-filed dispensing records from the Hcare system. Twenty-three community pharmacies were sampled from 2013 to 2015 to obtain records of patients above 65 years-old with continuous prescriptions. PIM were identified according to the 2015 Beers Criteria. The prevalence of patients using PIM was highest in patients with co-morbid mental disorders (40.05%), followed by neurological system disorders (28.91%). Patients who were prescribed a PIM were more than three times as likely to have a mental disorder as those (odds ratio 3.16, 95% confidence interval: 3.06-3.28) with non-chronic diseases. The most prescribed PIM agents were central nervous system drugs (53.16%), and benzodiazepines (35.15%). Patients with mental disorders had the highest rate of long-term persistent PIM exposure, with benzodiazepines being the most frequently dispensed. Drug safety concerns should be closely monitored in elderly patients with the abovementioned conditions.

Indexed as

Potentially Inappropriate Medication ListAgedAged, 80 and overChronic DiseaseComorbidityCross-Sectional StudiesFemaleGlycoside Hydrolase InhibitorsHumansIndependent LivingInfant, NewbornLiverMaleOdds RatioPrevalenceUrinalysisGlycoside Hydrolase InhibitorsBeers CriteriaChronic DiseaseElderlyPotentially Inappropriate Medication

Identifiers

PMID31226874
PMCPMC6616857
OpenAlexW2949860864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.