Evidence map›Paper›PMID 31226873›Full record

ArticleNutrients2019

Influence of Socio-Economic and Psychosocial Profiles on the Human Breast Milk Bacteriome of South African Women.

Anna Ojo-Okunola, Shantelle Claassen-Weitz, Kilaza S Mwaikono, Sugnet Gardner-Lubbe, Dan J Stein, Heather J Zar, Mark P Nicol, Elloise du Toit

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Anna Ojo-OkunolaDivision of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, Observatory 7925, University of Cape Town, Cape Town, South Africa. annas2343@gmail.com.
Shantelle Claassen-WeitzDivision of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, Observatory 7925, University of Cape Town, Cape Town, South Africa. tellafiela@gmail.com.
Kilaza S MwaikonoComputational Biology Group and H3ABioNet, Department of Integrative Biomedical Sciences, Observatory 7925, University of Cape Town, Cape Town, South Africa. kilazasmsn24@gmail.com.
Sugnet Gardner-LubbeDepartment of Statistics and Actuarial Science, Faculty of Economic and Management Sciences, Stellenbosch University, Matieland 7602, Stellenbosch, South Africa. slubbe@sun.ac.za.
Dan J SteinSA MRC Unit on Risk & Resilience in Mental Disorders, Dept of Psychiatry & Neuroscience Institute, Observatory 7925, University of Cape Town, Cape Town, South Africa. dan.stein@uct.ac.za.
Heather J ZarInstitute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, Observatory 7925, University of Cape Town, Cape Town, South Africa. heather.zar@uct.ac.za.
Mark P NicolDivision of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, Observatory 7925, University of Cape Town, Cape Town, South Africa. mark.nicol@uwa.edu.au.
Elloise du ToitDivision of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, Observatory 7925, University of Cape Town, Cape Town, South Africa. elloisedutoit@gmail.com.
University of Cape Town · ZAStellenbosch University · ZA

Funding

The nasopharyngeal microbiota of African children and lower respiratory tract infectionU54HG009824 · NHGRI · UNIVERSITY OF CAPE TOWN · PI NICOL, MARK PATRICK · 2017 to 2021
$2.9M
The nasopharyngeal microbiome and respiratory disease in African childrenU01AI110466 · NIAID · UNIVERSITY OF CAPE TOWN · PI NICOL, MARK PATRICK, ZAR, HEATHER JOY · 2013 to 2016
$1.4M
Bill and Melinda Gates Foundation OPP1017641; OPP1017579NHGRI NIH HHS U54 HG009824NIAID NIH HHS U01 AI110466NIH HHS 1U01AI110466-01A1NIH Office of the Director U54HG009824
6 · The paper itself

Abstract

The human breast milk (HBM) bacteriome is an important, continuous source of microbes to the neonate in early life, playing an important role in shaping the infant's intestinal bacteriome. Study of the composition of the HBM bacteriome is an emerging area of research, with little information available, particularly from low- and middle-income countries. The aim of this study was to characterize the diversity of bacterial communities in HBM samples collected between 6-10 weeks postpartum from lactating South African women and to study potential influencing factors of the bacteriome. Using 16S rRNA gene sequencing of samples from 554 women, we demonstrated that the HBM bacteriome was largely dominated by the phyla Firmicutes (mean relative abundance: 71.1%) and Actinobacteria (mean relative abundance: 16.4%). The most abundant genera identified from the HBM bacteriome were

Indexed as

MicrobiotaSocioeconomic FactorsAdultAge FactorsBacteriaBacteriological TechniquesFemaleHumansLactationMilk, HumanMothersRNA, Ribosomal, 16SSouth AfricaRNA, Ribosomal, 16S16S rRNA gene sequencingAfricabacterial profilesbacteriomeHuman breast milkmicrobiomepsychosocialsocio-economic

Identifiers

PMID31226873
PMCPMC6627120
OpenAlexW2953332535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.