ArticleMedicina (Kaunas, Lithuania)2019
Cleavage Stage versus Blastocyst Stage Embryo Transfer in Oocyte Donation Cycles.
Article in Medicina (Kaunas, Lithuania), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- In Vitro Fertilization Outcomes in Donor Oocyte Cycles Compared to the Autologous Cycles in the Poseidon 4 Group of Poor Ovarian Responders.Medicina (Kaunas, Lithuania) · 2025Article
- Stringent Regulations of Oocyte Donation Among Jewish Women in Israel: Characteristics and Outcomes of the National Oocyte Donation Program in One Central IVF Unit.Journal of religion and health · 2025Article
- When the Embryo Meets the Endometrium: Identifying the Features Required for Successful Embryo Implantation.International journal of molecular sciences · 2024Review
- The effect of gonadotropin-releasing hormone agonist downregulation in conjunction with hormone replacement therapy on endometrial preparation in patients for frozen-thawed embryo transfer.Frontiers in medicine · 2024Article
- Comparing the pregnancy outcomes of cleavage and blastocyst stage in frozen embryo transfer cycles: A cross-sectional study.International journal of reproductive biomedicine · 2023Article
- The pregnancy outcomes of day-5 poor-quality and day-6 high-quality blastocysts in single blastocyst transfer cycles.Clinical and experimental reproductive medicine · 2023Article
- When to Transfer Embryos if There Is Only 1 or 2?Life (Basel, Switzerland) · 2023Article
- D6 high-quality expanded blastocysts and D5 expanded blastocysts have similar pregnancy and perinatal outcomes following single frozen blastocyst transfer.Frontiers in endocrinology · 2023Article
- Commercially Available Molecular Approaches to Evaluate Endometrial Receptivity: A Systematic Review and Critical Analysis of the Literature.Diagnostics (Basel, Switzerland) · 2022Review
- Laser-assisted hatching on clinical and neonatal outcomes in patients undergoing single vitrified Blastocyst transfer: A propensity score-matched study.Reproductive medicine and biology · 2021Article
- Comparison of Pregnancy and Neonatal Outcomes of Single Frozen Blastocyst Transfer Between Letrozole-Induction and HRT Cycles in Patients With Abnormal Ovulation.Frontiers in endocrinology · 2021Article
- Pregnancy Outcomes of Single/Double Blastocysts and Cleavage Embryo Transfers: a Retrospective Cohort Study of 24,422 Frozen-Thawed Cycles.Reproductive sciences (Thousand Oaks, Calif.) · 2020Article
- D6 blastocyst transfer on day 6 in frozen-thawed cycles should be avoided: a retrospective cohort study.BMC pregnancy and childbirth · 2020Article
- Timing of frozen-thawed embryo transfers-does it really matter?Annals of translational medicine · 2020Article
- Random sperm DNA fragmentation index is not associated with clinical outcomes in day-3 frozen embryo transfer.Asian journal of andrologyArticle
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveDuring the last few years, a trend has been noted towards embryos being transferred at the blastocyst stage, which has been associated with improved rates regarding implantation and clinical pregnancy in comparison to cleavage stage embryo transfers. There is a limited number of studies investigating this notion in oocyte donation cycles employing cryopreserved embryos. The aim of this study is to evaluate the implantation potential and clinical pregnancy rates between the day 3 cleavage stage and blastocyst stage embryo transfers in oocyte donation cycles employing vitrified embryos.
methodsThis is a retrospective evaluation of oocyte donation frozen-thawed transfers completed in our clinic from January 2017 to December 2017. Intracytoplasmic sperm injection was conducted for all oocytes. Following fertilization, all embryos were cryopreserved either at the cleavage or blastocyst stage. Embryo transfer of two embryos was performed under direct sonographic guidance in all cases. Results
conclusionOur findings indicate that in oocyte donation cycles employing vitrified embryos, embryo transfer at the blastocyst stage is accompanied with a significant improvement in pregnancy rates and merits further investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.