Evidence map›Paper›PMID 31226817›Full record

ReviewInternational journal of molecular sciences2019

Anti-Cancer Agents in Proliferation and Cell Death: The Calcium Connection.

Elizabeth Varghese, Samson Mathews Samuel, Zuhair Sadiq, Peter Kubatka, Alena Liskova, Jozef Benacka, Peter Pazinka, Peter Kruzliak, Dietrich Büsselberg

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 126 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. International journal of molecular sciences · 2026
    Article
  8. Article
  9. Review
  10. Review
  11. Calcineurin in cancer signaling networks.Nagoya journal of medical science · 2025
    Review
  12. Review
  13. Article
  14. Article
  15. Management of Cardiac Rhythm Disorders in Cardio-oncology.Arrhythmia & electrophysiology review · 2025
    Review
  16. Review
  17. CaBiophysics reports · 2024
    Article
  18. Article
  19. TRPV1-Dependent Antiproliferative Activity of DioeciousInternational journal of molecular sciences · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Elizabeth VargheseDepartment of Physiology and Biophysics, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha P.O. Box 24144, Qatar. elv2007@qatar-med.cornell.edu.
Samson Mathews SamuelDepartment of Physiology and Biophysics, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha P.O. Box 24144, Qatar. sms2016@qatar-med.cornell.edu.ORCID 0000-0002-5541-6623
Zuhair SadiqDepartment of Physiology and Biophysics, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha P.O. Box 24144, Qatar. zuhairsadiq2018@u.northwestern.edu.ORCID 0000-0002-7692-6171
Peter KubatkaDepartment of Medical Biology and Department of Experimental Carcinogenesis, Division of Oncology, Biomedical Center Martin, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia. kubatka@jfmed.uniba.sk.ORCID 0000-0003-4312-5076
Alena LiskovaDepartment of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia. alenka.liskova@gmail.com.
Jozef BenackaFaculty Health and Social Work, Trnava University, 918 43 Trnava, Slovakia. jozef.benacka@centrum.cz.
Peter PazinkaDepartment of Surgery, Faculty of Medicine, Pavol Jozef Safarik University and Louise Pasteur University Hospital, 04022 Kosice, Slovakia. peter.pazinka@seznam.cz.
Peter KruzliakDepartment of Internal Medicine, Brothers of Mercy Hospital, Polni 553/3, 63900 Brno, Czech Republic. peter.kruzliak@savba.sk.
Dietrich BüsselbergDepartment of Physiology and Biophysics, Weill Cornell Medicine-Qatar, Education City, Qatar Foundation, Doha P.O. Box 24144, Qatar. dib2015@qatar-med.cornell.edu.ORCID 0000-0001-5196-3366
Weill Cornell Medical College in Qatar · QAComenius University Bratislava · SKMasaryk University · CZUniversity of Pavol Jozef Šafárik · SKUniversity of Trnava · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium (Ca

Indexed as

AnimalsAntineoplastic AgentsApoptosisCalciumCalcium SignalingCell ProliferationEndoplasmic ReticulumHumansMitochondriaMolecular Targeted TherapyNeoplasmsAntineoplastic AgentsCalciumanti-cancer drugsapoptosisIntracellular calciumproliferation

Identifiers

PMID31226817
PMCPMC6627763
OpenAlexW2949964993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.