Evidence map›Paper›PMID 31226795›Full record

ReviewInternational journal of molecular sciences2019

Mammalian Tyrosyl-DNA Phosphodiesterases in the Context of Mitochondrial DNA Repair.

Shar-Yin Naomi Huang, Yves Pommier

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Mitochondrial DNA Instability in Mammalian Cells.Antioxidants & redox signaling · 2022
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shar-Yin Naomi HuangDevelopmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA. shar-yin.huang@nih.gov.
Yves PommierDevelopmental Therapeutics Branch and Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA. pommier@nih.gov.
National Cancer Institute · US

Funding

Institut National Du Cancer Z01-BC 006161
6 · The paper itself

Abstract

Mammalian mitochondria contain four topoisomerases encoded in the nuclear genome: TOP1MT, TOP2α, TOP2β, and TOP3α. They also contain the two known tyrosyl-DNA phosphodiesterases (TDPs): TDP1 and TDP2, including a specific TDP2

Indexed as

DNA RepairAnimalsDNA-Binding ProteinsDNA DamageDNA, MitochondrialHumansMitochondriaNuclear ProteinsPhosphoric Diester HydrolasesTranscription FactorsDNA-Binding ProteinsDNA, MitochondrialNuclear ProteinsPhosphoric Diester HydrolasesTDP1 protein, humanTDP2 protein, humanTranscription Factorsantibiotics and antiviral agentscancermitochondrial DNAneurological disordersROSSCAN1TDP1TDP2topoisomerases

Identifiers

PMID31226795
PMCPMC6628236
OpenAlexW2949081726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.