ArticleInternational journal of environmental research and public health2019
Obesity and Polypharmacy among African American Older Adults: Gender as the Moderator and Multimorbidity as the Mediator.
Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 30 citations in OpenAlex.
- Body Mass Index Category and the Association Between Polypharmacy and Functional Recovery in Stroke Patients: A Retrospective Cohort Study.Drugs & aging · 2026Article
- Sexual dysfunction in male patients with obesity: is it still being overlooked?Hormones (Athens, Greece) · 2025Article
- EVALUATION OF SCREENING TOOL OF OLDER PEOPLE'S PRESCRIPTIONS (STOPP) CRITERIA IN AN URBAN COHORT OF OLDER PEOPLE WITH HIV.Pharmacoepidemiology · 2025Article
- Latent depressive profiles and associated factors among overweight/obese individuals based on the socio-ecological model: a cross-sectional national survey in China.Frontiers in psychology · 2025Article
- Gender Differences in the Association Between Socioeconomic Status and Cardiometabolic Health: National Health and Nutrition Examination Survey.Global journal of cardiovascular diseases · 2025Article
- Polypharmacy Is Associated with Sociodemographic Factors and Socioeconomic Status in United States Adults.Pharmacy (Basel, Switzerland) · 2024Article
- Polypharmacy and potentially inappropriate medicine use in older adults with cancer: a multicenter cross-sectional study in Northwest Ethiopia oncologic centers.Journal of pharmaceutical policy and practice · 2024Article
- Underweight, overweight, and weight change in older family caregivers and their care recipients: longitudinal evidence from a randomized controlled trial.Frontiers in aging · 2024Article
- Xenobiotic-Induced Aggravation of Metabolic-Associated Fatty Liver Disease.International journal of molecular sciences · 2022Review
- A Qualitative Analysis to Understand Perception about Medication-Related Problems among Older Minority Adults in a Historically Black Community.Pharmacy (Basel, Switzerland) · 2022Article
- Analysis of the regional difference in the number of multi-drug prescriptions and its predictors in Japan, 2015-2018.BMC research notes · 2021Article
- A cross-sectional study of financial distress in persons with multimorbidity.Preventive medicine reports · 2021Article
- Fat-Fit Patterns, Drug Consumption, and Polypharmacy in Older Adults: The EXERNET Multi-Center Study.Nutrients · 2021Article
- DNA methylation and exposure to violence among African American young adult males.Brain, behavior, & immunity - health · 2021Article
- Lessons Learned in Nutrition Therapy in Patients With Severe COVID-19.JPEN. Journal of parenteral and enteral nutrition · 2020Article
- Nucleus Accumbens Functional Connectivity with the Frontoparietal Network Predicts Subsequent Change in Body Mass Index for American Children.Brain sciences · 2020Article
- Medication Complexity among Disadvantaged African American Seniors in Los Angeles.Pharmacy (Basel, Switzerland) · 2020Article
- Psychotropic and Opioid-Based Medication Use among Economically Disadvantaged African-American Older Adults.Pharmacy (Basel, Switzerland) · 2020Article
- Polypharmacy Is Associated with Lower Memory Function in African American Older Adults.Brain sciences · 2020Article
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Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Despite high prevalence of obesity and polypharmacy among African American (AA) older adults, little information exists on the associations between the two in this population. This study explored the association between obesity and polypharmacy among AA older adults who were residing in poor urban areas of South Los Angeles. We also investigated role of gender as the moderator and multimorbidity as the mediator of this association. In a community-based study in South Los Angeles, 308 AA older adults (age ≥ 55 years) were entered into this study. From this number, 112 (36.4%) were AA men and 196 (63.6%) were AA women. Polypharmacy (taking 5+ medications) was the dependent variable, obesity was the independent variable, gender was the moderator, and multimorbidity (number of chronic medical conditions) was the mediator. Age, educational attainment, financial difficulty (difficulty paying bills, etc.), income, marital status, self-rated health (SRH), and depression were the covariates. Logistic regressions were used for data analyses. In the absence of multimorbidity in the model, obesity was associated with higher odds of polypharmacy in the pooled sample. This association was not significant when we controlled for multimorbidity, suggesting that multimorbidity mediates the obesity-polypharmacy link. We found significant association between obesity and polypharmacy in AA women not AA men, suggesting that gender moderates such association. AA older women with obesity are at a higher risk of polypharmacy, an association which is mainly due to multimorbidity. There is a need for screening for inappropriate polypharmacy in AA older women with obesity and associated multimorbidity.
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Registered trials
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