Evidence map›Paper›PMID 31226484›Full record

ArticleGenomics2020

Phylogenetic determinants of toxin gene distribution in genomes of Brevibacillus laterosporus.

Travis R Glare, Abigail Durrant, Colin Berry, Leopoldo Palma, M Marsha Ormskirk, Murray P Cox

Open access · hybridAbstract read
In one paragraph

Article in Genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  5. Multiple S-Layer Proteins ofInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Travis R GlareBio-Protection Research Centre, PO Box 85084, Lincoln University, Lincoln, New Zealand. Electronic address: travis.glare@lincoln.ac.nz.
Abigail DurrantBio-Protection Research Centre, PO Box 85084, Lincoln University, Lincoln, New Zealand.
Colin BerryCardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, UK.
Leopoldo PalmaUniversidad Nacional de Villa María, Instituto A.P. de Ciencias Básicas y Aplicadas, Av. Arturo Jauretche 1555, Villa María 5900, Córdoba, Argentina.
M Marsha OrmskirkBio-Protection Research Centre, PO Box 85084, Lincoln University, Lincoln, New Zealand.
Murray P CoxStatistics and Bioinformatics Group, Institute of Fundamental Sciences, Massey University, Palmerston North 4410, New Zealand.
Lincoln University · NZCardiff University · GBMassey University · NZNational University of Villa María · AR

Funding

Wellcome TrustWellcome Trust 090532/Z/09/Z
6 · The paper itself

Abstract

Brevibacillus laterosporus is a globally ubiquitous, spore forming bacterium, strains of which have shown toxic activity against invertebrates and microbes and several have been patented due to their commercial potential. Relatively little is known about this bacterium. Here, we examined the genomes of six published and five newly determined genomes of B. laterosporus, with an emphasis on the relationships between known and putative toxin encoding genes, as well as the phylogenetic relationships between strains. Phylogenetically, strain relationships are similar using average nucleotide identity (ANI) values and multi-gene approaches, although PacBio sequencing revealed multiple copies of the 16S rDNA gene which lessened utility at the strain level. Based on ANI values, the New Zealand isolates were distant from other isolates and may represent a new species. While all of the genomes examined shared some putative toxicity or virulence related proteins, many specific genes were only present in a subset of strains.

Indexed as

Anti-Infective AgentsBacterial ProteinsBacterial ToxinsBiosynthetic PathwaysBrevibacillusGenes, BacterialGenome, BacterialHigh-Throughput Nucleotide SequencingPhylogenyPlasmidsVirulenceAnti-Infective AgentsBacterial ProteinsBacterial ToxinsBacillalesGenomesPhylogenyToxinsVirulence

Identifiers

PMID31226484
PMCPMC6978878
OpenAlexW2953002042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.