Evidence map›Paper›PMID 31226244›Full record

ArticleeLife2019

optoPAD, a closed-loop optogenetics system to study the circuit basis of feeding behaviors.

José-Maria Moreira, Pavel M Itskov, Dennis Goldschmidt, Celia Baltazar, Kathrin Steck, Ibrahim Tastekin, Samuel J Walker, Carlos Ribeiro

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Dual roles ofiScience · 2025
    Article
  6. Article
  7. Review
  8. Exitron splicing of odor receptor genes inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Serotonergic control of feeding microstructure inFrontiers in behavioral neuroscience · 2022
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Behavior Individuality: A Focus onFrontiers in physiology · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

José-Maria Moreira *Champalimaud Centre for the Unknown, Lisbon, Portugal.ORCID 0000-0003-2420-7930
Pavel M Itskov *Champalimaud Centre for the Unknown, Lisbon, Portugal.ORCID 0000-0002-2191-7083
Dennis Goldschmidt *Champalimaud Centre for the Unknown, Lisbon, Portugal.ORCID 0000-0002-0603-7176
Celia BaltazarChampalimaud Centre for the Unknown, Lisbon, Portugal.
Kathrin SteckChampalimaud Centre for the Unknown, Lisbon, Portugal.ORCID 0000-0003-2711-2873
Ibrahim TastekinChampalimaud Centre for the Unknown, Lisbon, Portugal.
Samuel J WalkerChampalimaud Centre for the Unknown, Lisbon, Portugal.ORCID 0000-0003-3118-8467
Carlos RibeiroChampalimaud Centre for the Unknown, Lisbon, Portugal.ORCID 0000-0002-9542-7335

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
NIH HHS P40 OD018537
6 · The paper itself

Abstract

The regulation of feeding plays a key role in determining the fitness of animals through its impact on nutrition. Elucidating the circuit basis of feeding and related behaviors is an important goal in neuroscience. We recently used a system for closed-loop optogenetic manipulation of neurons contingent on the feeding behavior of

Indexed as

OptogeneticsAnimalsDrosophila melanogasterFeeding BehaviorNeuronsTasteTaste PerceptionbehaviorD. melanogasterfeedingmethodsneuroscienceoptogeneticstaste

Identifiers

PMID31226244
PMCPMC6589098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.