ArticlePloS one2019
Sex-based differences in multidimensional clinical assessments of early-abstinence crack cocaine users.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Effects of substance use disorder on oxidative and antioxidative stress markers: A systematic review and meta-analysis.Addiction biology · 2023Pooled it
- Sex chromosome genes contribute to cocaine vulnerability in a strain-dependent manner.Research square · 2026Article
- Lipidomic and proteomic insights from extracellular vesicles in the postmortem dorsolateral prefrontal cortex reveal substance use disorder-induced brain changes.Translational psychiatry · 2025Article
- Sex differences in stress-modulated cocaine vulnerability: female rodents are more sensitive to the effects of stress exposure at different developmental stages.Frontiers in behavioral neuroscience · 2025Review
- Sex-specific effects of chronic stress prior to cocaine exposure on cue- vs drug-induced relapse after prolonged abstinence.Behavioural brain research · 2024Article
- Examining predictors of cocaine withdrawal syndrome at the end of detoxification treatment in women with cocaine use disorder.Journal of psychiatric research · 2024Article
- Plasma Lysophosphatidic Acid Concentrations in Sex Differences and Psychiatric Comorbidity in Patients with Cocaine Use Disorder.International journal of molecular sciences · 2023Article
- The importance of translationally evaluating steroid hormone contributions to substance use.Frontiers in neuroendocrinology · 2023Review
- Sexual violence against men in Brazil: underreporting, prevalence, and associated factors.Revista de saude publica · 2023Review
- Gender differences in progression to crack-cocaine use and the role of sexual and physical violence.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2022Article
- The Perceptions of Women About Their High Experience of Using Crack Cocaine.Frontiers in psychiatry · 2022Article
- Influence of gender and education on cocaine users in an outpatient cohort in Spain.Scientific reports · 2021Article
- White matter deficits in cocaine use disorder: convergent evidence from in vivo diffusion tensor imaging and ex vivo proteomic analysis.Translational psychiatry · 2021Article
- Activation of G-protein coupled estradiol receptor 1 in the dorsolateral striatum attenuates preference for cocaine and saccharin in male but not female rats.Hormones and behavior · 2021Article
- Application of the Chinese version of the addiction profile index (API) in drug users: an analysis of validity and measurement invariance across genders.Substance abuse treatment, prevention, and policy · 2020Article
- Prediction of attempted suicide in men and women with crack-cocaine use disorder in Brazil.PloS one · 2020Article
- Cocaine use disorder in females is associated with altered social decision-making: a study with the prisoner's dilemma and the ultimatum game.BMC psychiatry · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
Crack cocaine use disorder (CUD) has been related to sex differences. This work aimed to compare the severity of drug use and the severity of other negative related outcomes in males and females with CUD. A total of 1344 inpatients (798 males and 546 females) with crack cocaine use disorder (CUD) were evaluated by a detailed multidimensional clinical assessment, including addiction severity and trauma exposure. Linear regression predicted higher drug use severity (β = 0.273, p < 0.001) and more problems in domains related to childcare issues (β = 0.321), criminal involvement (β = 0.108), work-related problems (β = 0.281) and social support impairments (β = 0.142) for females, all with p < 0.001. Alcohol problems were predicted to be higher in males (β = -0.206, P < 0.001). Females had higher rates of other mental disorders, particularly trauma and stress-related disorders (OR: 3.206, CI: 2.22, 4.61). Important sex differences also emerged in trauma history and HIV infection prevalence. CUD has a more severe clinical presentation among females facing early abstinence. Sex differences in the CUD course indicate the need for consideration of sex-specific interventions and research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.