Evidence map›Paper›PMID 31226109›Full record

ArticlePLoS neglected tropical diseases2019

Standardized endocystectomy technique for surgical treatment of uncomplicated hepatic cystic echinococcosis.

Mohammed Al-Saeedi, Elias Khajeh, Katrin Hoffmann, Omid Ghamarnejad, Marija Stojkovic, Tim F Weber, Mohammad Golriz, Oliver Strobel, Thomas Junghanss, Markus W Büchler and 1 more

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Evaluation of Hydatid Cyst Antigen for Serological Diagnosis.Medical journal of the Islamic Republic of Iran · 2023
    Article
  8. Observational
  9. Article
  10. Article
  11. Reply to Akbulut et al.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Mohammed Al-SaeediDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Elias KhajehDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Katrin HoffmannDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Omid GhamarnejadDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Marija StojkovicSection of Clinical Tropical Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Tim F WeberDepartment of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.ORCID 0000-0001-5911-123X
Mohammad GolrizDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Oliver StrobelDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Thomas JunghanssSection of Clinical Tropical Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Markus W BüchlerDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Arianeb MehrabiDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.ORCID 0000-0001-6163-1525
Heidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTwo surgical options are available for cystic echinococcosis (CE). The two principal approaches are radical (resection of the cyst) and conservative (evacuation of the cyst content and partial removal of the cyst capsule). Here, we describe a standardized endocystectomy technique for hepatic echinococcosis. SUBJECTS AND

methodsTwenty-one patients (male/female: 4/3; median age: 28 years) with uncomplicated, isolated hepatic CE (cyst stages WHO CE1, 2, 3a, and 3b) that were treated with the standardized endocystectomy described in this paper. Before the operation and during the follow-up period (mean: 33.8 months, median: 24 months), patients underwent clinical and sonographical and/or magnetic resonance imaging assessment during regular visits managed by an interdisciplinary team.

resultsForty-seven cysts were treated with the standardized endocystectomy technique. The median number of cysts per patient was two (range: 1-8). Nine patients (43%) had a single cystic lesion. The median operation time was 165 minutes and the median intraoperative bleeding volume was 200 mL. The median hospital stay was nine days (range: 6-28 days). Morbidity (Clavien-Dindo III) occurred in four patients (19%). No mortality and no recurrence were found during the median follow-up time of 24 months.

conclusionsThe standardized endocystectomy technique presented is a safe procedure with acceptable morbidity, no mortality, and without recurrences in our patient series. Important components of our CE management are interdisciplinary patient care, adequate diagnostic work-ups, and regular pre- and postoperative visits, including long-term follow-up for early and reliable capture of recurrences.

Indexed as

AdolescentAdultAgedEchinococcosis, HepaticEndoscopyFemaleHumansMaleMiddle AgedRecurrenceSurvival AnalysisTreatment OutcomeYoung Adult

Identifiers

PMID31226109
PMCPMC6608982
OpenAlexW2950909446

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.