ArticleAmerican journal of physiology. Heart and circulatory physiology2019
Central and peripheral factors mechanistically linked to exercise intolerance in heart failure with reduced ejection fraction.
Article in American journal of physiology. Heart and circulatory physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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Who cites it
28 citing papers in PubMed, 32 citations in OpenAlex.
- Effects of Lifestyle-Integrated Active Pursed-Lip Diaphragmatic Breathing Training on the Prognosis of Chronic Heart Failure: A Retrospective Real-World Study.Healthcare (Basel, Switzerland) · 2026Article
- Effects of soluble guanylyl cyclase stimulation on muscle oxygenation and exercise capacity in heart failure with mildly reduced ejection fraction.Experimental physiology · 2026Article
- Bulk and regional diaphragm blood flow during chemical hyperpnea in pulmonary hypertensive rats.Respiratory physiology & neurobiology · 2025Article
- Blue plaque review series: A.V. Hill, athletic records and the birth of exercise physiology.The Journal of physiology · 2025Article
- Skeletal and respiratory muscle blood flow redistribution during submaximal exercise in pulmonary hypertensive rats.The Journal of physiology · 2025Article
- Exercise pre-conditioning prevents vascular toxicity caused by infusion of 5-fluorouracil in male rats.American journal of cancer research · 2025Article
- Tumor bearing in untreated breast cancer decreases exercise tolerance without lowering maximal oxygen uptake in rats.American journal of cancer research · 2025Article
- The treatment of chronic anemia in heart failure: a global approach.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Review
- Pulmonary hypertension impairs vasomotor function in rat diaphragm arterioles.Microvascular research · 2024Article
- Vascular dysfunction and the age-related decline in critical power.Experimental physiology · 2024Article
- IFN-γ and androgens disrupt mitochondrial function in murine myocytes.The Journal of pathology · 2023Article
- Pulmonary hypertension alters blood flow distribution and impairs the hyperemic response in the rat diaphragm.Frontiers in physiology · 2023Article
- Effects of pulmonary hypertension on microcirculatory hemodynamics in rat skeletal muscle.Microvascular research · 2022Article
- Capillary hemodynamics and contracting skeletal muscle oxygen pressures in male rats with heart failure: Impact of soluble guanylyl cyclase activator.Nitric oxide : biology and chemistry · 2022Article
- Oxygen flux from capillary to mitochondria: integration of contemporary discoveries.European journal of applied physiology · 2022Review
- The effects of pulmonary hypertension on skeletal muscle oxygen pressures in contracting rat spinotrapezius muscle.Experimental physiology · 2021Article
- Authors' Reply to Ibai García-Tabar and Esteban M. Gorostiaga: Comment on "Relative Proximity of Critical Power and Metabolic/Ventilatory Thresholds: Systematic Review and Meta-Analysis".Sports medicine (Auckland, N.Z.) · 2021Article
- Sexual dimorphism in vascular ATP-sensitive KThe Journal of physiology · 2021Article
- Exaggerated sympathetic and cardiovascular responses to dynamic mechanoreflex activation in rats with heart failure: Role of endoperoxide 4 and thromboxane AAutonomic neuroscience : basic & clinical · 2021Article
- Angiotensin converting enzyme inhibition improves cerebrovascular control during exercise in male rats with heart failure.Respiratory physiology & neurobiology · 2021Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exercise intolerance is a primary symptom of heart failure (HF); however, the specific contribution of central and peripheral factors to this intolerance is not well described. The hyperbolic relationship between exercise intensity and time to exhaustion (speed-duration relationship) defines exercise tolerance but is underused in HF. We tested the hypotheses that critical speed (CS) would be reduced in HF, resting central functional measurements would correlate with CS, and the greatest HF-induced peripheral dysfunction would occur in more oxidative muscle. Multiple treadmill-constant speed runs to exhaustion were used to quantify CS and D' (distance coverable above CS) in healthy control (Con) and HF rats. Central function was determined via left ventricular (LV) Doppler echocardiography [fractional shortening (FS)] and a micromanometer-tipped catheter [LV end-diastolic pressure (LVEDP)]. Peripheral O
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.