Observational studyNeurourology and urodynamics2019
A new outcome measure for LUTS: Symptoms of Lower Urinary Tract Dysfunction Research Network Symptom Index-29 (LURN SI-29) questionnaire.
Observational study in Neurourology and urodynamics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
AMPLIFY: Amplifying Sensation in Underactive Bladder
Turkish Validity and Reliability of LURN SI-29 Questionnaire Form in Patients With Lower Urinary Tract Symptoms
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Patient-reported outcome measures for pain in women with pelvic floor disorders: a systematic review.International urogynecology journal · 2022Pooled it
- Ecological Momentary Assessment Reveals Greater Anxiety and Marked Instability of Urinary Urgency in Overactive Bladder.International urogynecology journal · 2026Article
- The LURN Urinary Urgency and Lifestyle Wearable Tracker (ULTra) study: Design and feasibility.Continence (Amsterdam, Netherlands) · 2026Article
- Generalized Sensory Sensitivity in Patients With Urinary Urgency-A LURN II Urinary Urgency Phenotyping Study.The Journal of urology · 2026Article
- Patients With Urinary Urgency Have Central Sensitization Symptoms-A LURN II Phenotyping Study.The Journal of urology · 2026Article
- Evaluating the Lower Urinary Tract Dysfunction Research Network Symptom Index-29 and SI-10 for Lower Urinary Tract Symptom Assessment Against with the International Prostate Symptom Score: A Cross-Cultural Validation and Agreement Study.Urology research & practice · 2026Article
- Gaps in patient-reported outcome measures integration into the management of lower urinary tract symptoms attributed to benign prostatic hyperplasia (LUTS/BPH): qualitative insights for implementation strategies.Journal of patient-reported outcomes · 2026Article
- Symptoms and subtypes of patients with lower urinary tract dysfunction - insights from the Symptoms of Lower Urinary Tract Dysfunction Research Network.Nature reviews. Urology · 2026Review
- Reliability and validity of Arabic version of Lower Urinary Tract Dysfunction Research Network Symptom Index-10 questionnaire (LURN SI-10).World journal of urology · 2026Article
- Shared Decision Making, Decision Aids and Patient Reported Outcome Measures for Overactive Bladder Care: A Review.Current bladder dysfunction reports · 2026Review
- Development and implementation of a nurse-led clinical decision support tool for urinary tract infection.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Safety and efficacy of aquablation in men 80 years or older: an analysis of the international collaborative aquablation research urology society (ICARUS) real-world database.World journal of urology · 2025Article
- Patient Related Outcomes for Interstitial Cystitis/Bladder Pain Syndrome Recommendations for Clinical Trials and General Urology Practice.Neurourology and urodynamics · 2025Review
- The Mobility and Voiding Exercises in Older Women with Urinary Incontinence (MoVEonUp) randomized controlled trial: study protocol and rationale.BMC geriatrics · 2024Article
- Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN): An introduction to the Urinary Urgency Phenotyping Protocol LURN II.Neurourology and urodynamics · 2024Review
- Developing a urinary incontinence primary care pathway: a mixed methods study.Family practice · 2024Article
- The Spider: a visual, multisystemic symptom impact questionnaire for people with hypermobility-related disorders-validation in adults.Clinical rheumatology · 2024Observational
- Lower Urinary Tract Symptoms in US Women: Contemporary Prevalence Estimates from the RISE FOR HEALTH Study.The Journal of urology · 2024Article
- Enhanced clinical decisions for management of benign prostatic hyperplasia using patient-reported outcomes: protocol for a prospective observational study.BMC urology · 2024Observational
- Enhanced Clinical Decisions for Management of Benign Prostatic Hyperplasia using Patient-Reported Outcomes: Protocol for a Prospective Observational Study.Research square · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 9 institutions in 1 country.
Funding
Abstract
aimsTo develop a representative, self-report assessment of lower urinary tract symptoms (LUTS) for men and women, the symptoms of Lower Urinary Tract Dysfunction Research Network Symptom Index-29 (LURN SI-29).
methodsWomen and men seeking treatment for LUTS at one of six academic medical centers in the US were assessed at baseline, 3-month and 12-month intervals. Twelve-month data on 78 LURN SI-29 items were analyzed among 353 women and 420 men using exploratory factor analysis (EFA), with factor structure confirmed using confirmatory factor analysis (CFA). Internal consistency, reliability, and validity of the five developed scales were evaluated by assessing correlations with the American Urological Association Symptom Index (AUA-SI), the genitourinary pain index (GUPI), and the Pelvic Floor Distress Inventory-20 (PFDI-20), and by examining expected sex differences in scores.
resultsEFA results (n = 150 women; 150 men) produced an interpretable eight-factor solution, with three of the factors comprised of dichotomous items addressing LUTS-associated sensations. The remaining five factors, confirmed with CFA in an independent sample of 473 participants, produced five scales: incontinence, urgency, voiding difficulty, bladder pain, and nocturia. Subscales and total LURN SI-29 scores were correlated as expected with AUA-SI, GUPI, and PFDI-20. LURN SI-29 scores also performed as expected in differentiating men from women based upon clinically expected differences, with men reporting more voiding difficulties and nocturia, and women reporting more urgency and incontinence.
conclusionsThe LURN SI-29 questionnaire has the potential to improve research and clinical outcome measurement for both men and women with LUTS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.