Evidence map›Paper›PMID 31225794›Full record

ArticleeLife2019

Voluntary and involuntary contributions to perceptually guided saccadic choices resolved with millisecond precision.

Emilio Salinas, Benjamin R Steinberg, Lauren A Sussman, Sophia M Fry, Christopher K Hauser, Denise D Anderson, Terrence R Stanford

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Trajectories of Response Inhibition Development in Adolescence.bioRxiv : the preprint server for biology · 2026
    Article
  3. Rapid Motor Inhibition as a Mechanism to Prevent Outdated Movements.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  4. Contributions of Distinct Attention Mechanisms to Saccadic Choices in a Gamified, Dynamic Environment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Coupling of saccade plans to endogenous attention during urgent choices.bioRxiv : the preprint server for biology · 2024
    Article
  13. Article
  14. Common and distinct neural mechanisms of attention.Trends in cognitive sciences · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emilio SalinasDepartment of Neurobiology and Anatomy, Wake Forest School of Medicine, Winston-Salem, United States.ORCID 0000-0001-7411-5693
Benjamin R SteinbergDepartment of Neurobiology and Anatomy, Wake Forest School of Medicine, Winston-Salem, United States.
Lauren A SussmanDepartment of Neurobiology and Anatomy, Wake Forest School of Medicine, Winston-Salem, United States.
Sophia M FryDepartment of Neurobiology and Anatomy, Wake Forest School of Medicine, Winston-Salem, United States.
Christopher K HauserDepartment of Neurobiology and Anatomy, Wake Forest School of Medicine, Winston-Salem, United States.
Denise D AndersonDepartment of Neurobiology and Anatomy, Wake Forest School of Medicine, Winston-Salem, United States.
Terrence R StanfordDepartment of Neurobiology and Anatomy, Wake Forest School of Medicine, Winston-Salem, United States.

Funding

CRCNS: investigating perceptual processing speed and its impact on choice behaviorR01EY025172 · NEI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SALINAS, EMILIO, STANFORD, TERRENCE R · 2016 to 2024
$3.6M
Midbrain Mechanisms of Sensory-Guided Oculomotor ChoiceR01EY021228 · NEI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SALINAS, EMILIO, STANFORD, TERRENCE R · 2014 to 2017
$1.8M
Training Program in Multisensory ProcessesT32NS073553 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI STEIN, BARRY E · 2011 to 2020
$1.7M
National Science Foundation Graduate research fellowshipNEI NIH HHS R01 EY021228NEI NIH HHS R01EY021228NEI NIH HHS R01 EY025172NEI NIH HHS R01EY025172NINDS NIH HHS T32 NS073553NINDS NIH HHS T32NS073553-01
6 · The paper itself

Abstract

In the antisaccade task, which is considered a sensitive assay of cognitive function, a salient visual cue appears and the participant must look away from it. This requires sensory, motor-planning, and cognitive neural mechanisms, but what are their unique contributions to performance, and when exactly are they engaged? Here, by manipulating task urgency, we generate a psychophysical curve that tracks the evolution of the saccadic choice process with millisecond precision, and resolve the distinct contributions of reflexive (exogenous) and voluntary (endogenous) perceptual mechanisms to antisaccade performance over time. Both progress extremely rapidly, the former driving the eyes toward the cue early on (∼100 ms after cue onset) and the latter directing them away from the cue ∼40 ms later. The behavioral and modeling results provide a detailed, dynamical characterization of attentional and oculomotor capture that is not only qualitatively consistent across participants, but also indicative of their individual perceptual capacities.

Indexed as

AdultCuesFemaleHumansMaleModels, BiologicalMotor ActivitySaccadesTask Performance and AnalysisTime FactorsVisual PerceptionYoung Adultattentiondecision makinghumanindividual differencesmental chronometryneurosciencesalience

Identifiers

PMID31225794
PMCPMC6645714

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.