Evidence map›Paper›PMID 31225653›Full record

ArticleImmunology2019

Regulatory T cells in cancer: where are we now?

Awen Gallimore, Sergio A Quezada, Rahul Roychoudhuri

Abstract readEditorial
In one paragraph

Article in Immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Frontiers in molecular biosciences · 2022
    Article
  7. A Darwinian perspective on tumor immune evasion.Biochimica et biophysica acta. Reviews on cancer · 2022
    Review
  8. Review
  9. Article
  10. Article
  11. Clinical Significance ofPathology oncology research : POR · 2021
    Article
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Awen GallimoreDivision of Infection and Immunity, Cardiff University, Cardiff, UK.
Sergio A QuezadaCancer Immunology Unit, University College London (UCL) Cancer Institute, London, UK.
Rahul RoychoudhuriLaboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/N007794/1Biotechnology and Biological Sciences Research Council BBS/E/B/000C0407Biotechnology and Biological Sciences Research Council BBS/E/B/000C0409Cancer Research UK 16463Cancer Research UK 20764Cancer Research UK 21200Cancer Research UK 22246Cancer Research UK 22597Cancer Research UK C52623/A22597Medical Research Council MC_UP_1502/3Medical Research Council MR/S024468/1Wellcome TrustWellcome Trust 105663/Z/14/Z
6 · The paper itself

Abstract

There have been substantial strides forward in our understanding of the contribution of regulatory T (Treg) cells to cancer immunosuppression. In this issue, we present a series of papers highlighting emerging themes on this topic relevant not only to our understanding of the fundamental biology of tumour immunosuppression but also to the design of new immunotherapeutic approaches. The substantially shared biology of CD4

Indexed as

Tumor EscapeAnimalsHumansImmunotherapyLymphocytes, Tumor-InfiltratingNeoplasmsPhenotypeSignal TransductionT-Lymphocytes, Regulatory

Identifiers

PMID31225653
PMCPMC6587319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.