Evidence map›Paper›PMID 31225520›Full record

ArticleWorld neurosurgery: X2019

Linear Accelerator-Based Radiosurgery of Grade I Intracranial Meningiomas.

Sara Alatriste-Martínez, Sergio Moreno-Jiménez, Guillermo A Gutiérrez-Aceves, José de Jesús Suárez-Campos, Olivia Amanda García-Garduño, Alejandro Rosas-Cabral, Miguel Ángel Celis-López

Abstract read
In one paragraph

Article in World neurosurgery: X, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sara Alatriste-MartínezRadioneurosurgery Unit, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico.
Sergio Moreno-JiménezRadioneurosurgery Unit, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico.
Guillermo A Gutiérrez-AcevesRadioneurosurgery Unit, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico.
José de Jesús Suárez-CamposRadioneurosurgery Unit, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico.
Olivia Amanda García-GarduñoRadioneurosurgery Unit, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico.
Alejandro Rosas-CabralDepartment of Medicine, Universidad Autónoma de Aguascalientes, Aguascalientes, Mexico.
Miguel Ángel Celis-LópezRadioneurosurgery Unit, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the local control rate and complication rate in the treatment of grade I intracranial meningiomas.

methodsA retrospective study was performed of patients with grade I meningioma who received radiosurgery with a dedicated linear accelerator from January 2002 to August 2012 with a minimum follow-up of 2 years. We performed descriptive statistics, logistic regression, and progression-free survival analysis through a Kaplan-Meier curve.

resultsSeventy-five patients with 78 grade I meningiomas received radiosurgery, 39 underwent surgery plus adjuvant radiosurgery, and 36 only radiosurgery. The follow-up median time was 68 months (range, 35-120 months). The tumor control rate was 93%, the 5-year progression-free survival was 92% (95% confidence interval, 77%-98%). Acute toxicity was 2.6%, and grade 1-2 late toxicity was 26.6%. Postradiosurgery edema was the main late morbidity. Age >55 years was the only significant factor for attaining a response >75%. The background of surgery before radiosurgery was the only significant prognostic factor for showing edema (odds ratio 5.78 [95% confidence interval, 2.14-15.64]).

conclusionsThe local control rate attained in our series is similar to that reported in other series worldwide; the acute toxicity rate was low and late toxicity was moderate.

Indexed as

Benign tumorsCBK, CyberKnifeGKRS, Gamma Knife radiosurgeryLINAC, Linear acceleratorLINAC radiosurgeryMeningiomasMRI, Magnetic resonance imagingPFS, Progression-free survivalRS, RadiosurgeryWHO, World Health Organization

Identifiers

PMID31225520
PMCPMC6584458

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.