Evidence map›Paper›PMID 31225451›Full record

ArticleCell stress2018

Intravital imaging tumor screen used to identify novel metastasis-blocking therapeutic targets.

Konstantin Stoletov, Lian Willetts, Perrin H Beatty, John D Lewis

Open access · goldAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell stress, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Konstantin StoletovDepartment of Oncology, University of Alberta, Edmonton, Alberta, Canada, T6G 2E1.
Lian WillettsDepartment of Oncology, University of Alberta, Edmonton, Alberta, Canada, T6G 2E1.
Perrin H BeattyDepartment of Oncology, University of Alberta, Edmonton, Alberta, Canada, T6G 2E1.
John D LewisDepartment of Oncology, University of Alberta, Edmonton, Alberta, Canada, T6G 2E1.
University of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer cell motility is a key driver of metastasis. Although the intravasation of cancer cells into the blood stream is highly dependent on their motility and metastatic dissemination is the primary cause of cancer related deaths, current therapeutic strategies do not target the genes and proteins that are essential for cell motility. A primary reason for this is because the identification of cell motility-related genes that are relevant

Indexed as

ex ovo chick embryo modelfluorescence time-lapse intravital imaginghigh throughput sequencingintravasationmetastaticc cancershRNA librarytherapeutic targets

Identifiers

PMID31225451
PMCPMC6551637
OpenAlexW2894609516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.