Evidence map›Paper›PMID 31223565›Full record

ReviewIranian journal of public health2019

Cultured Epidermal Melanocyte Transplantation in Vitiligo: A Review Article.

Shaghayegh Zokaei, Dariush D Farhud, Mohammad Keykhaei, Marjan Zarif Yeganeh, Hoda Rahimi, Hamideh Moravvej

Open access · goldAbstract readReview
In one paragraph

Review in Iranian journal of public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Stimulatory effects ofFrontiers in pharmacology · 2023
    Article
  5. Review
  6. Surgical Treatment of Vitiligo.International journal of environmental research and public health · 2022
    Review
  7. Article
  8. Article
  9. Review
  10. Non-cultured melanocyte transfer in the management of stable vitiligo.Journal of family medicine and primary care · 2019
    Article
  11. Hearing status in patients with vitiligo.Clinical, cosmetic and investigational dermatology · 2019
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shaghayegh ZokaeiSchool of Advanced Medical Sciences, Islamic Azad University, Tehran Medical Branch, Tehran, Iran.
Dariush D FarhudSchool of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad KeykhaeiSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Marjan Zarif YeganehCellular and Molecular Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hoda RahimiSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Hamideh MoravvejSkin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahid Beheshti University of Medical Sciences · IRTehran University of Medical Sciences · IRIslamic Azad University Medical Branch of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe color of the skin is highly heritable but can be influenced by the environments and endocrine factors. Many other factors, sometimes destructive, are also involved in the formation of skin color, which sometimes affects pigmentation patterns. Vitiligo is an autoimmune hypopigmentation painless disorder with appearance of white patches and psychological effects on patients. It is a disease in which melanocytes of the skin are destroyed in certain areas; therefore depigmentation appears.

methodsWe studied more than 60 articles. Several therapeutic methods have been used to return the color of skin in vitiligo. These methods include non-invasive treatment and surgical techniques. Among all these therapies, cell transplantation is an advanced procedure in regenerative medicine. Extraction of melanocytes from normal skin and then their cultivation in the laboratory provides a large number of these cells, the transplanting of which to depigmentation areas stimulates the site to irreversibly produce melanin.

resultsThe transplantation methods of these cells have been evolved over many years and the methods of producing blister have been changed to the injection of these cells to the target sites.

conclusionIn this review, autologous cultured melanocyte transplantation has been considered to be the most viable, safe, and effective method in the history of vitiligo treatments.

Indexed as

Autologous cultured melanocytesMelanocyteMelanocyte transplantationRepigmentationVitiligo

Identifiers

PMID31223565
PMCPMC6570809
OpenAlexW2939274059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.