Evidence map›Paper›PMID 31223556›Full record

ArticleCurrent epidemiology reports2017

Addressing Bias in Electronic Health Record-Based Surveillance of Cardiovascular Disease Risk: Finding the Signal Through the Noise.

Julie K Bower, Sejal Patel, Joyce E Rudy, Ashley S Felix

Abstract read
In one paragraph

Article in Current epidemiology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Review
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  7. Modern sources of controls in case-control studies.American journal of epidemiology · 2025
    Article
  8. Article
  9. Observational
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julie K BowerDivision of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH.
Sejal PatelDivision of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH.
Joyce E RudyDivision of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH.
Ashley S FelixDivision of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH.

Funding

Women's Health Initiative Cancer Survivor CohortUM1CA173642 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ANDERSON, GARNET L., CAAN, BETTE J · 2013 to 2018
$12.1M
NCI NIH HHS UM1 CA173642
6 · The paper itself

Abstract

purpose of reviewUse of the electronic health record (EHR) for CVD surveillance is increasingly common. However, these data can introduce systematic error that influences the internal and external validity of study findings. We reviewed recent literature on EHR-based studies of CVD risk to summarize the most common types of bias that arise. Subsequently, we recommend strategies informed by work from others as well as our own to reduce the impact of these biases in future research. RECENT

findingsSystematic error, or bias, is a concern in all observational research including EHR-based studies of CVD risk surveillance. Patients captured in an EHR system may not be representative of the general population, due to issues such as informed presence bias, perceptions about the healthcare system that influence entry, and access to health services. Further, the EHR may contain inaccurate information or be missing key data points of interest due to loss to follow-up or over-diagnosis bias. Several strategies, including implementation of unique patient identifiers, adoption of standardized rules for inclusion/exclusion criteria, statistical procedures for data harmonization and analysis, and incorporation of patient-reported data have been used to reduce the impact of these biases. SUMMARY: EHR data provide an opportunity to monitor and characterize CVD risk in populations. However, understanding the biases that arise from EHR datasets is instrumental in planning epidemiological studies and interpreting study findings. Strategies to reduce the impact of bias in the context of EHR data can increase the quality and utility of these data.

Indexed as

biascardiovascular diseaseelectronic health recordepidemiologyrisk factors

Identifiers

PMID31223556
PMCPMC6585457

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.