Evidence map›Paper›PMID 31223275›Full record

ArticleInternational journal of biological sciences2019

HJURP Promotes Epithelial-to-Mesenchymal Transition via Upregulating SPHK1 in Hepatocellular Carcinoma.

Tianchi Chen, Lingfeng Zhou, Yuan Zhou, Wuhua Zhou, Hechen Huang, Shengyong Yin, Haiyang Xie, Lin Zhou, Shusen Zheng

Abstract read
In one paragraph

Article in International journal of biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  16. Holliday Cross-Recognition ProteinPathology oncology research : POR · 2022
    Article
  17. Article
  18. MicroRNA-596 is epigenetically inactivated and suppresses prostatic cancer cell growth and migration via regulating Wnt/β-catenin signaling.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tianchi ChenDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Lingfeng ZhouDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Yuan ZhouNHFPC Key Laboratory of Combined Multi-organ Transplantation, Hangzhou, China.
Wuhua ZhouNHFPC Key Laboratory of Combined Multi-organ Transplantation, Hangzhou, China.
Hechen HuangNHFPC Key Laboratory of Combined Multi-organ Transplantation, Hangzhou, China.
Shengyong YinNHFPC Key Laboratory of Combined Multi-organ Transplantation, Hangzhou, China.
Haiyang XieNHFPC Key Laboratory of Combined Multi-organ Transplantation, Hangzhou, China.
Lin ZhouNHFPC Key Laboratory of Combined Multi-organ Transplantation, Hangzhou, China.
Shusen ZhengDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Holliday Junction Recognition Protein (HJURP) is involved in various cancers including hepatocellular carcinoma (HCC). Current studies have showed that HJURP is correlated with HCC proliferation. However, the role of HJURP in HCC Epithelial-to-Mesenchymal Transition remains unclear. In this study, we found that HJURP knockdown significantly reduced the migration and invasion abilities of HCC cells both

Indexed as

Epithelial-Mesenchymal TransitionAdaptor Proteins, Signal TransducingCarcinoma, HepatocellularCell Line, TumorDNA-Binding ProteinsHumansLiver NeoplasmsNeoplasm MetastasisUp-RegulationAdaptor Proteins, Signal TransducingDNA-Binding ProteinsHJURP protein, humanSPHKAP protein, humanepithelial-to-mesenchymal transitionhepatocellular carcinomaHolliday junction recognition proteinsphingosine kinase 1

Identifiers

PMID31223275
PMCPMC6567799

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.