Evidence map›Paper›PMID 31223047›Full record

ReviewImmunological investigations2019

Evolutionary Underpinnings of Innate-Like T Cell Interactions with Cancer.

Maureen Banach, Jacques Robert

Open access · greenAbstract readReview
In one paragraph

Review in Immunological investigations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Biology · 2023
    Review
  3. Article
  4. Review
  5. Introduction.Immunological investigations · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Maureen BanachDepartment of Immunology & Microbiology, University of Colorado School of Medicine , Aurora , CO , USA.
Jacques RobertDepartment of Microbiology & Immunology, University of Rochester Medical Center , Rochester , NY , USA.
University of Colorado Denver · USUniversity of Rochester Medical Center · US

Funding

A Xenopus Laevis Research Resource for ImmunologyR24AI059830 · NIAID · UNIVERSITY OF ROCHESTER · PI JACQUES Robert · 2004 to 2026
$7.7M
The role of The Xenopus Nonclassical MHC class I molecule XNC10 in Tumor ImmunityF31CA192664 · NCI · UNIVERSITY OF ROCHESTER · PI BANACH, MAUREEN LUDMILA · 2015 to 2018
$153k
NCI NIH HHS F31 CA192664NIAID NIH HHS R24 AI059830
6 · The paper itself

Abstract

Cancers impose a significant health and economic burden. By harnessing the immune system, current immunotherapies have revolutionized the treatment against human cancers and potentially offer a long-term cure. Among others, innate-like T (iT) cells, including natural killer T cells, are promising candidates for immunotherapies. Unlike conventional T cells, iT cells regulate multiple immune processes and express an invariant T cell receptor that is shared among different individuals. However, the conditions that activate the pro- and antitumor functions of iT cells are partially understood. These gaps in knowledge hamper the use of iT cell in clinics. It might be beneficial to examine the roles of iT cells in an alternative animal model - the amphibian

Indexed as

Biological EvolutionDisease Models, AnimalAnimalsHistocompatibility Antigens Class IHumansNatural Killer T-CellsNeoplasmsReceptors, Antigen, T-CellXenopus laevisHistocompatibility Antigens Class IReceptors, Antigen, T-Cellcancer immunityevolutionmhc1b10.1.LMHC-I likeNKT cellsTumor immunityunconventional T cells

Identifiers

PMID31223047
PMCPMC6699903
OpenAlexW2951599018

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.