ReviewJournal of diabetes investigation2019
Painful and non-painful diabetic polyneuropathy: Clinical characteristics and diagnostic issues.
Review in Journal of diabetes investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Redefining distal symmetrical polyneuropathy features in type 1 diabetes: a systematic review.Acta diabetologica · 2022Pooled it
- Cervical spinal cord enlargement and systemic inflammation in diabetic peripheral neuropathy: a cross-sectional MRI study.Irish journal of medical science · 2026Article
- Lidocaine alleviates diabetic neuropathic pain by inhibiting spinal astrocyte activation through modulation of the CXCL13/CXCR5 axis.Journal of molecular histology · 2026Article
- Exploring core and sentinel symptoms in elderly patients with type 2 diabetes through network analysis and the Apriori algorithm.Frontiers in medicine · 2026Article
- Diabetic Neuropathic Pain Models: Current Limitations and Future Directions.Journal of pain research · 2026Review
- A Multicenter, Prospective, Observational, and Single-Arm Interventional Study of Mirogabalin in Diabetic Peripheral Neuropathic Pain: Rationale and Design of Dia-NeP.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Article
- Clinical Phenotypes of Diabetic Peripheral Neuropathy: Implications for Phenotypic-Based Therapeutics Strategies.Diabetes & metabolism journal · 2025Review
- Is Exercise Enough? Integrating Pharmacological and Physical Therapy Approaches in the Management of Diabetic Polyneuropathy - A Narrative Review.Journal of pharmacy & bioallied sciences · 2025Article
- Intravenous Streptozotocin Induces Variants in Painful Diabetic Peripheral Neuropathy in Female Mice.Journal of pain research · 2025Article
- Therapeutic Interventions for Diabetes Mellitus-associated Complications.Current diabetes reviews · 2025Review
- A Conceptual Model of Patient Experiences of Painful Diabetic Peripheral Neuropathy to Support Clinical Outcomes Assessment.Journal of pain research · 2025Article
- Phase Angle of Bioelectrical Impedance Analysis as an Indicator for Diabetic Polyneuropathy in Type 2 Diabetes Mellitus.The Journal of clinical endocrinology and metabolism · 2024Observational
- Effect of 28 days treatment of baricitinib on mechanical allodynia, osteopenia, and loss of nerve fibers in an experimental model of type-1 diabetes mellitus.Pharmacological reports : PR · 2024Article
- A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled 14-Week Study of Mirogabalin in Chinese Patients with Diabetic Peripheral Neuropathic Pain.Pain and therapy · 2024Article
- Assessment of neuropathy subtypes in type 1 diabetes.BMJ open diabetes research & care · 2024Article
- Recent Advances in Biomolecular Patho-Mechanistic Pathways behind the Development and Progression of Diabetic Neuropathy.Biomedicines · 2024Review
- Aldose reductase is a potential therapeutic target for neurodegeneration.Chemico-biological interactions · 2024Review
- Role of microglia in diabetic neuropathic pain.Frontiers in cell and developmental biology · 2024Review
- Expert opinion on screening, diagnosis and management of diabetic peripheral neuropathy: a multidisciplinary approach.Frontiers in endocrinology · 2024Review
- Why too soon? Predictors of time to diabetic peripheral neuropathy among newly diagnosed diabetes mellitus patients: a multicenter follow-up study at health-care setting of Ethiopia.Archives of public health = Archives belges de sante publique · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Diabetic neuropathy (DN) is a common complication of diabetes and can be either painful or non-painful. It is challenging to diagnose this complication, as no biomarker or clear consensus on the clinical definition of either painful or non-painful DN exists. Hence, a hierarchical classification has been developed categorizing the probability of the diagnosis into: possible, probable or definite, based on the clinical presentation of symptoms and signs. Pain is a warning signal of tissue damage, and non-painful DN therefore represents a clinical and diagnostic challenge because it often goes unnoticed until irreversible nerve damage has occurred. Simple clinical tests seem to be the best for evaluation of DN in the general care for diabetes. Screening programs at regular intervals might be the most optimal strategy for early detection and interventions to possibly prevent further neuronal damage and to lower the economic burden of this complication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.