Evidence map›Paper›PMID 31222727›Full record

ArticleAnaesthesia2019

The development and validation of the Score for the Prediction of Postoperative Respiratory Complications (SPORC-2) to predict the requirement for early postoperative tracheal re-intubation: a hospital registry study.

C Lukannek, S Shaefi, K Platzbecker, D Raub, P Santer, S Nabel, H S Lecamwasam, T T Houle, M Eikermann

Abstract readMulticenter StudyValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Anaesthesia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

C LukannekDepartment of Anaesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
S ShaefiAnesthesia Information Systems, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
K PlatzbeckerAnesthesia Information Systems, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
D RaubDepartment of Anaesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
P SanterAnesthesia Information Systems, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
S NabelAnesthesia Information Systems, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
H S LecamwasamDepartment of Anesthesia, Rhode Island Hospital and Warren Alpert Medical School of Brown University, Providence, RI, USA.
T T HouleDepartment of Anaesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
M EikermannDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.

Funding

Sepsis and the benefits of permissive hypoxiaK08GM134220 · NIGMS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SHAEFI, SHAHZAD · 2019 to 2022
$775k
Proteomic Analysis of Postoperative Delirium from a randomized trial in Older Patients undergoing Cardiac Surgery exposed to Intraoperative Normoxia versus Hyperoxia: A Nested Case-Control StudyR03AG060179 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SHAEFI, SHAHZAD · 2018 to 2019
$263k
NIA NIH HHS R03 AG060179NIGMS NIH HHS K08 GM134220
6 · The paper itself

Abstract

Postoperative pulmonary complications are associated with an increase in mortality, morbidity and healthcare utilisation. The Agency for Healthcare Research and Quality recommends risk assessment for postoperative respiratory complications in patients undergoing surgery. In this hospital registry study of adult patients undergoing non-cardiac surgery between 2005 and 2017 at two independent healthcare networks, a prediction instrument for early postoperative tracheal re-intubation was developed and externally validated. This was based on the development of the Score for Prediction Of Postoperative Respiratory Complications. For predictor selection, stepwise backward logistic regression and bootstrap resampling were applied. Development and validation cohorts were represented by 90,893 patients at Partners Healthcare and 67,046 patients at Beth Israel Deaconess Medical Center, of whom 699 (0.8%) and 587 (0.9%) patients, respectively, had their tracheas re-intubated. In addition to five pre-operative predictors identified in the Score for Prediction Of Postoperative Respiratory Complications, the final model included seven additional intra-operative predictors: early post-tracheal intubation desaturation; prolonged duration of surgery; high fraction of inspired oxygen; high vasopressor dose; blood transfusion; the absence of volatile anaesthetic use; and the absence of lung-protective ventilation. The area under the receiver operating characteristic curve for the new score was significantly greater than that of the original Score for Prediction Of Postoperative Respiratory Complications (0.84 [95%CI 0.82-0.85] vs. 0.76 [95%CI 0.75-0.78], respectively; p < 0.001). This may allow clinicians to develop and implement strategies to decrease the risk of early postoperative tracheal re-intubation.

Indexed as

Intubation, IntratrachealFemaleHospitalsHumansLungMaleMiddle AgedPostoperative ComplicationsRegistriesReproducibility of ResultsRespiration DisordersRisk Factorsclinical epidemiologycritical carepostoperative ventilationquality measuresrisk assessment

Identifiers

PMID31222727
PMCPMC7424553

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.