Evidence map›Paper›PMID 31222675›Full record

ArticleJournal of the American Society for Mass Spectrometry2019

Mapping Unsaturation in Human Plasma Lipids by Data-Independent Ozone-Induced Dissociation.

David L Marshall, Angela Criscuolo, Reuben S E Young, Berwyck L J Poad, Martin Zeller, Gavin E Reid, Todd W Mitchell, Stephen J Blanksby

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 67 citations in OpenAlex.

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  3. Analytical applications of gas-phase ion chemistry enabled by mass spectrometry.Analytical methods : advancing methods and applications · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

David L MarshallCentral Analytical Research Facility, Institute for Future Environments, Queensland University of Technology, Brisbane, QLD, 4000, Australia. d20.marshall@qut.edu.au.ORCID http://orcid.org/0000-0002-1711-2338
Angela CriscuoloInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Universität Leipzig, Leipzig, Germany.
Reuben S E YoungSchool of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology, Brisbane, Australia.
Berwyck L J PoadCentral Analytical Research Facility, Institute for Future Environments, Queensland University of Technology, Brisbane, QLD, 4000, Australia.
Martin ZellerThermo Fisher Scientific (Bremen) GmbH, Hanna-Kunath Str. 11, 28199, Bremen, Germany.
Gavin E ReidSchool of Chemistry, Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Australia.
Todd W MitchellSchool of Medicine and Molecular Horizons, University of Wollongong, Wollongong, Australia.
Stephen J BlanksbyCentral Analytical Research Facility, Institute for Future Environments, Queensland University of Technology, Brisbane, QLD, 4000, Australia. stephen.blanksby@qut.edu.au.
Queensland University of Technology · AUThermo Fisher Scientific (Germany) · DEIllawarra Health and Medical Research Institute · AUUniversity of Melbourne · AU

Funding

Australian Research Council DP150101715Australian Research Council DP190101486H2020 Marie Skłodowska-Curie Actions 675132
6 · The paper itself

Abstract

Over 1500 different lipids have been reported in human plasma at the sum composition level. Yet the number of unique lipids present is surely higher, once isomeric contributions from double bond location(s) and fatty acyl regiochemistry are considered. In order to resolve this ambiguity, herein, we describe the incorporation of ozone-induced dissociation (OzID) into data-independent shotgun lipidomics workflows on a high-resolution hybrid quadrupole-Orbitrap platform. In this configuration, [M + Na]

Indexed as

Cholesterol EstersHumansLipidsOzoneSpectrometry, Mass, Electrospray IonizationTandem Mass SpectrometryWorkflowCholesterol EstersLipidsOzoneData-independent analysisLipidomicsOzone-induced dissociationPlasma

Identifiers

PMID31222675
OpenAlexW2949529460

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.