ArticleInternational journal of behavioral medicine2020
Positive and Negative Affect and Salivary Markers of Inflammation Among Young Adults.
Article in International journal of behavioral medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- The effect of acute stress on salivary markers of inflammation: A systematic review and meta-analysis.Brain, behavior, and immunity · 2020Pooled it
- C-Reactive Protein in Saliva as a Non-Invasive Marker of Metabolic Syndrome: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2026Review
- [A two-sample Mendelian randomization study on the association between temporomandibular disorder and insomnia].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025Article
- Role of inflammation in depressive and anxiety disorders, affect, and cognition: genetic and non-genetic findings in the lifelines cohort study.Translational psychiatry · 2025Article
- Salivary Biomarkers of Inflammation in Patients With Chronic Non-Specific Low Back Pain.Biomarker insights · 2025Article
- The Relationship of Neighborhood Disadvantage, Biological Aging, and Psychosocial Risk and Resilience Factors in Heart Failure Incidence Among Black Persons: A Moderated Mediation Analysis.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Validation of a novel method of ultraviolet-induced cutaneous inflammation and its associations with anhedonia.Scientific reports · 2022Article
- Individuals with both higher recent negative affect and physical pain have higher levels of C-reactive protein.Brain, behavior, & immunity - health · 2022Article
- Disparity of Gut Microbiota Composition Among Elite Athletes and Young Adults With Different Physical Activity Independent of Dietary Status: A Matching Study.Frontiers in nutrition · 2022Article
- The Role of Salivary C-Reactive Protein in Systemic and Oral Disorders: A Systematic Review.Medical journal of the Islamic Republic of Iran · 2022Review
- From childhood maltreatment to adult inflammation: Evidence for the mediational status of social anxiety and low positive affect.Brain, behavior, & immunity - health · 2021Article
- Measuring salivary markers of inflammation in health research: A review of methodological considerations and best practices.Psychoneuroendocrinology · 2021Review
- Comparison of C-Reactive Protein in Dried Blood Spots and Saliva of Healthy Adolescents.Frontiers in immunology · 2021Article
- Positive affect and peripheral inflammatory markers among adults: A narrative review.Psychoneuroendocrinology · 2021Review
- Intraindividual Variability in Sleep and Levels of Systemic Inflammation in Nurses.Psychosomatic medicine · 2020Article
- Physiometrics in Salivary Bioscience.International journal of behavioral medicine · 2020Article
- Salivary Bioscience and the Future of Behavioral Medicine.International journal of behavioral medicine · 2020Article
- Aging as a Context for the Role of Inflammation in Depressive Symptoms.Frontiers in psychiatry · 2020Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundEmerging evidence suggests that higher circulating levels of inflammatory biomarkers in blood are associated with higher negative affect (NA) and lower positive affect (PA). To our knowledge, the unique associations between NA and PA in daily life and salivary biomarkers of inflammation have not been examined. This study examined these associations in young adults.
methodsMeasures of NA and PA were created from aggregated daily measures of affect (morning and evening ratings averaged across 14 days). We investigated associations between these measures and salivary C-reactive protein (CRP) and interleukin (IL)-6 in a sample of 108 young adults (60% female, mean age = 20.45 ± 1.47), a subset of whom had self-reported chronic back pain (n = 49). CRP and IL-6 were determined from saliva obtained at the end of the daily diary period.
resultsAfter covarying for age, gender, body mass index, chronic pain status, salivary flow rate, and NA, higher PA was associated with lower salivary CRP (β = - 0.02, 95% CI (- 0.03, - 0.00) sr
conclusionsFindings suggest that higher PA may be associated with lower salivary CRP in young adults, even after accounting for NA and demographic characteristics. Findings highlight the utility of assessing emotional states in relation to salivary markers of inflammation in future biobehavioral research.
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Registered trials
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