Evidence map›Paper›PMID 31222591›Full record

ArticleSleep & breathing = Schlaf & Atmung2020

Electrocardiogram-based sleep analysis for sleep apnea screening and diagnosis.

Yan Ma, Shuchen Sun, Ming Zhang, Dan Guo, Arron Runzhou Liu, Yulin Wei, Chung-Kang Peng

Open access · greenAbstract readComparative Study
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
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  4. Association of self-reported and objective sleep disturbance with the spectrum of gastroesophageal reflux disease.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
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  10. ECG Patient Simulator Based on Mathematical Models.Sensors (Basel, Switzerland) · 2022
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Yan MaCenter for Dynamical Biomarkers, Division of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA, 02215, USA. dr.yan.ma@gmail.com.ORCID http://orcid.org/0000-0003-1173-2920
Shuchen SunDepartment of Otolaryngology and South Campus Sleep Center, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China. sunsc0922@163.com.
Ming ZhangNanjing Integrated Traditional Chinese and Western Medicine Hospital, Nanjing, 210000, China.
Dan GuoCenter for Dynamical Biomarkers, Division of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA, 02215, USA.
Arron Runzhou LiuCenter for Dynamical Biomarkers, Division of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA, 02215, USA.
Yulin WeiChina-Japan Friendship Hospital, Beijing, 100029, China.
Chung-Kang PengCenter for Dynamical Biomarkers, Division of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA, 02215, USA.
Beth Israel Deaconess Medical Center · USChina-Japan Friendship Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNNanjing Traditional Chinese Medicine Hospital · CN

Funding

Research Training in Complementary and Integrative MedicineT32AT000051 · NCCIH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GLORIA Y YEH · 1999 to 2026
$10.2M
National Natural Science Foundation of China 81273820NCCIH NIH HHS T32 AT000051NIH HHS T32AT000051
6 · The paper itself

Abstract

purposeDespite the increasing number of research studies of cardiopulmonary coupling (CPC) analysis, an electrocardiogram-based technique, the use of CPC in underserved population remains underexplored. This study aimed to first evaluate the reliability of CPC analysis for the detection of obstructive sleep apnea (OSA) by comparing with polysomnography (PSG)-derived sleep outcomes.

methodsTwo hundred five PSG data (149 males, age 46.8 ± 12.8 years) were used for the evaluation of CPC regarding the detection of OSA. Automated CPC analyses were based on ECG signals only. Respiratory event index (REI) derived from CPC and apnea-hypopnea index (AHI) derived from PSG were compared for agreement tests.

resultsCPC-REI positively correlated with PSG-AHI (r = 0.851, p < 0.001). After adjusting for age and gender, CPC-REI and PSG-AHI were still significantly correlated (r = 0.840, p < 0.001). The overall results of sensitivity and specificity of CPC-REI were good.

conclusionCompared with the gold standard PSG, CPC approach yielded acceptable results among OSA patients. ECG recording can be used for the screening or diagnosis of OSA in the general population.

Indexed as

AdultAgedAutonomic Nervous SystemElectrocardiographyFemaleHumansMaleMass ScreeningMiddle AgedOutcome Assessment, Health CarePolysomnographyReproducibility of ResultsSleep Apnea, ObstructiveAutonomic nervous systemCardiopulmonary couplingElectrocardiogramObstructive sleep apneaPolysomnographyPortable monitoring

Identifiers

PMID31222591
PMCPMC6925360
OpenAlexW2951853875

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.