Evidence map›Paper›PMID 31222530›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021

Head-to-head comparison of diagnostic accuracy of stress-only myocardial perfusion imaging with conventional and cadmium-zinc telluride single-photon emission computed tomography in women with suspected coronary artery disease.

Teresa Mannarino, Roberta Assante, Carlo Ricciardi, Emilia Zampella, Carmela Nappi, Valeria Gaudieri, Ciro Gabriele Mainolfi, Eugenio Di Vaia, Mario Petretta, Mario Cesarelli and 2 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Gender Medicine in Clinical Radiology Practice.Journal of personalized medicine · 2023
    Review
  3. Imaging of heart disease in women: review and case presentation.European journal of nuclear medicine and molecular imaging · 2022
    Review
  4. Beyond equality, women require extra care in cardiovascular imaging.European journal of nuclear medicine and molecular imaging · 2022
    Article
  5. Article
  6. Prone-only SPECT myocardial perfusion imaging: An alternative standard in clinical practice?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  7. Article
  8. Article
  9. A machine learning-based approach to directly compare the diagnostic accuracy of myocardial perfusion imaging by conventional and cadmium-zinc telluride SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  10. Article
  11. Quantification of myocardial perfusion reserve by CZT-SPECT: A head to head comparison withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  12. Advanced technology in the risk stratification-based strategy: The way forward to keep going.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  13. Review
  14. Article
  15. Did we solve soft tissue (breast) attenuation?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  16. Myocardial perfusion reserve by using CZT: It's a long way to the top if you wanna standardize.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Teresa Mannarino *Department of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Roberta Assante *Department of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Carlo RicciardiDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Emilia ZampellaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Carmela NappiDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Valeria GaudieriDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Ciro Gabriele MainolfiDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Eugenio Di VaiaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Mario PetrettaDepartment of Translational Medical Sciences, University Federico II, Naples, Italy.
Mario CesarelliDepartment of Electrical Engineering and Information Technology, University Federico II, Naples, Italy.
Alberto CuocoloDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Wanda AcampaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy. acampa@unina.it.
Federico II University Hospital · ITInstitute of Biostructure and Bioimaging · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast attenuation may impact the diagnostic accuracy of stress myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT). We compared the performance of conventional (C)-SPECT and cadmium-zinc-telluride (CZT)-SPECT systems in women with low-intermediate likelihood of coronary artery disease (CAD). METHODS AND

resultsA total of 109 consecutive women underwent stress-optional rest MPI by both C-SPECT and CZT-SPECT. In the overall study population, a weak albeit significant correlation between total perfusion defect (TPD) measured by C-SPECT and CZT-SPECT was observed (r = 0.38, P < .001) and at Bland-Altman analysis the mean difference in TPD (C-SPECT minus CZT-SPECT) was 2.40% (P < .001). Overall concordance of semi-quantitative diagnostic performance between C-SPECT and CZT-SPECT was observed in 52 (48%) women with a κ value of 0.09. Normalcy rate was significantly higher using CZT-SPECT compared to C-SPECT (P < .001). Machine learning analysis performed through the implementation of J48 algorithm proved that CZT-SPECT has higher sensitivity, specificity, and accuracy than C-SPECT.

conclusionsIn women with low-intermediate likelihood of CAD, there is a poor concordance of diagnostic performance between C-SPECT and CZT-SPECT, and CZT-SPECT allows better normalcy rate detection compared to C-SPECT.

Indexed as

CadmiumTelluriumZincAgedCoronary AngiographyCoronary Artery DiseaseElectrocardiographyExercise TestFemaleGamma CamerasHumansImage Processing, Computer-AssistedMachine LearningMiddle AgedMyocardial Perfusion ImagingPerfusionCadmiumCdZnTeTelluriumZincCADDiagnostic applicationMPISPECT

Identifiers

PMID31222530
OpenAlexW2951214349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.