ReviewNeuroscience bulletin2020
Connections Between Insomnia and Cognitive Aging.
Review in Neuroscience bulletin, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 64 citations in OpenAlex.
- NADAlzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Multimodal MRI radiomics and deep learning for brain age prediction: age-corrected brain age gap analysis in patients with insomnia.Biomedical engineering online · 2026Article
- Interpretable machine learning models for identifying cognitive impairment in middle-aged and older adults with mild and severe insomnia: development, temporal validation, and clinical external validation.Frontiers in aging neuroscience · 2026Article
- Age Differences in Factors Associated With Insomnia Severity: A Comparative Study of Questionnaire Scores and Heart Rate Variability Parameters.Depression and anxiety · 2026Article
- Mechanisms of Senegenin in Regulating Oxidative Stress and Mitochondria Damage for Neuroprotection in Insomnia: Evidence from In Vivo and In Vitro Models.Molecular neurobiology · 2025Article
- Predictors and Factors Associated with Insomnia in a Brazilian Sample: A Cross-Sectional Study.Sleep science (Sao Paulo, Brazil) · 2025Article
- Senegenin regulates the mechanism of insomnia through the Keap1/Nrf2/PINK1/Parkin pathway mediated by GAD67.Journal of sleep research · 2025Article
- Daytime Sleepiness, Apnea, Neuroimaging Correlates and Cortisol Dysregulation in a Memory Clinic Cohort.The journal of prevention of Alzheimer's disease · 2024Article
- Linking Adverse Childhood Experiences and Other Risk Factors to Subjective Cognitive Decline in an Aging Population.Preventing chronic disease · 2023Article
- Protocol for a randomized controlled trial exploring the brain mechanism and therapeutic effect of electroacupuncture on cognitive function and sleep quality in chronic insomnia.BMC complementary medicine and therapies · 2023Article
- Article
- Detection of Insomnia and Its Relationship with Cognitive Impairment, Depression, and Quality of Life in Older Community-Dwelling Mexicans.Diagnostics (Basel, Switzerland) · 2023Article
- Mental and physical health pathways linking insomnia symptoms to cognitive performance 14 years later.Sleep · 2023Article
- Review
- P2X7 receptor-activated microglia in cortex is critical for sleep disorder under neuropathic pain.Frontiers in neuroscience · 2023Article
- A bibliometric analysis of the application of imaging in sleep in neurodegenerative disease.Frontiers in aging neuroscience · 2023Article
- Race Differences in the Association Between Sleep Medication Use and Risk of Dementia.Journal of Alzheimer's disease : JAD · 2023Article
- Study on the Mechanism of Jiaotai Pill Intervention on Insomnia Animal Model Based on Gut Microbiome and Metabolomics.Evidence-based complementary and alternative medicine : eCAM · 2023Article
- The Relationship Between Cognitive Impairments and Sleep Quality Measures in Persistent Insomnia Disorder.Nature and science of sleep · 2023Article
- Short sleeping duration is associated with a higher risk of asymmetric handgrip strength among older Chinese males: a cross-sectional study evidence from the China health and retirement longitudinal study.Frontiers in public health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
Insomnia is a common sleep disorder among older adults, and a risk factor for poor physical and mental health. However, the relationship between insomnia and cognitive health is not well understood. Here, we review observational studies that have investigated whether insomnia is associated with deficits in objective cognitive performance and an increased risk of dementia, magnetic resonance imaging studies that have assessed grey matter volumes and white matter microstructure, and interventional studies that have explored whether the treatment of insomnia can improve cognitive outcomes. There are inconsistent findings regarding impaired performance in objective cognitive tests and reduced grey matter volumes, and limited, emerging, evidence that suggests that insomnia is associated with an increased risk of dementia and reduced white matter integrity. Although the interventional literature is still in its infancy, there is some indication that treatment may have an impact on vigilance. Well-powered studies examining sources of heterogeneity are warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.