Evidence map›Paper›PMID 31222481›Full record

ArticleLasers in medical science2020

Photobiomodulation increases cell viability via AKT activation in an in vitro model of diabetes induced by glucose neurotoxicity.

Victória Regina da Silva Oliveira, Rosangela Aparecida Santos-Eichler, Camila Squarzoni Dale

Abstract read
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In one paragraph

Article in Lasers in medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Victória Regina da Silva OliveiraLaboratory of Neuromodulation of Pain, Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, Av. Professor Lineu Prestes 2415, ICB III, Cidade Universitária, São Paulo, 05508-000, Brazil.
Rosangela Aparecida Santos-EichlerLaboratory of Intracellular Peptides Pharmacology, Department of Pharmacology, University of São Paulo, Av Lineu Prestes 1524, ICB I, São Paulo, 05508-900, Brazil.
Camila Squarzoni DaleLaboratory of Neuromodulation of Pain, Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, Av. Professor Lineu Prestes 2415, ICB III, Cidade Universitária, São Paulo, 05508-000, Brazil. camila.dale@usp.br.ORCID http://orcid.org/0000-0002-3421-7799
Universidade de São Paulo · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/17136-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2016/10372-0
6 · The paper itself

Abstract

Peripheral neuropathy (PN) is a serious complication of diabetes mellitus (DM) and is known to be resistant to conventional treatment. Photobiomodulation (PBM) is demonstrated to be effective in treating PN and in protecting nerve fiber damage. To better understand the mechanisms underlying the regenerative effects of PBM on diabetic neuropathy, we conducted a study in an in vitro model of diabetes induced by glucose neurotoxicity. Neuro 2A cells (1 × 10

Indexed as

Low-Level Light TherapyAnimalsCell Line, TumorCell SurvivalDiabetic NeuropathiesEnzyme ActivationGlucoseL-Lactate DehydrogenaseMiceNeuronal OutgrowthProto-Oncogene Proteins c-aktGlucoseL-Lactate DehydrogenaseProto-Oncogene Proteins c-aktDiabetesneuro2A cellsPhotobiomodulationρ-AKT

Identifiers

PMID31222481
OpenAlexW2953023663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.