ReviewCurrent neurology and neuroscience reports2019
Hereditary Sensory and Autonomic Neuropathies: Adding More to the Classification.
Review in Current neurology and neuroscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Neurotrophic keratopathy in childhood: advances in understanding of pathogenesis and management.Eye (London, England) · 2026Review
- Expanding the Genetic Landscape of Congenital Insensitivity to Pain.Neurology. Genetics · 2026Article
- Rare autosomal recessive hereditary sensory and autonomic neuropathy type VI in a Pakistani family caused by a novel DST variant.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Review
- Hereditary Sensory and Autonomic Neuropathy Type 2: A Case Report and a Review of the Literature.Brain sciences · 2025Article
- The transcriptional landscape of the developing chick trigeminal ganglion.Developmental biology · 2025Article
- Spectrum of neuropathic skeletal injuries in children: a pictorial essay.Insights into imaging · 2025Article
- Modeling of Charcot-Marie-Tooth disease in zebrafish.Frontiers in molecular neuroscience · 2025Review
- Development of autonomic heart rate modulations during childhood and adolescence.Pflugers Archiv : European journal of physiology · 2024Article
- Homozygosity for a RareInternational journal of molecular sciences · 2024Article
- Autoimmune Autonomic Neuropathy: From Pathogenesis to Diagnosis.International journal of molecular sciences · 2024Review
- Familial dysautonomia.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023Review
- Living without pain. Case series of patients with hereditary sensory and autonomic neuropathies in a Canadian tertiary care centre.Paediatrics & child health · 2023Article
- A mysterious triangle of blood, bones, and nerves.Journal of bone and mineral metabolism · 2023Review
- Case report: Hereditary sensory autonomic neuropathy presenting as bifid deformity to the tongue.Frontiers in dental medicine · 2023Article
- Orthopedic Manifestations of Hereditary Sensory and Autonomic Neuropathy IV in a 10-Year-Old Patient.The Iowa orthopaedic journal · 2023Article
- Congenital insensitivity to pain associated withFrontiers in genetics · 2023Article
- Reduced penetrance of an eastern French mutation in ATL1 autosomal-dominant inheritance (SPG3A): extended phenotypic spectrum coupled with brainNeurogenetics · 2022Article
- Pathophysiology of Nociception and Rare Genetic Disorders with Increased Pain Threshold or Pain Insensitivity.Pathophysiology : the official journal of the International Society for Pathophysiology · 2022Review
- Loss of Elp1 disrupts trigeminal ganglion neurodevelopment in a model of familial dysautonomia.eLife · 2022Article
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Authors and funding
2 authors.
Funding
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Abstract
purpose of reviewHereditary sensory and autonomic neuropathies (HSANs) are a clinically heterogeneous group of inherited neuropathies featuring prominent sensory and autonomic involvement. Classification of HSAN is based on mode of inheritance, genetic mutation, and phenotype. In this review, we discuss the recent additions to this classification and the important updates on management with a special focus on the recently investigated disease-modifying agents. RECENT
findingsIn this past decade, three more HSAN types were added to the classification creating even more diversity in the genotype-phenotype. Clinical trials are underway for disease-modifying and symptomatic therapeutics, targeting mainly HSAN type III. Obtaining genetic testing leads to accurate diagnosis and guides focused management in the setting of such a diverse and continuously growing phenotype. It also increases the wealth of knowledge on HSAN pathophysiologies which paves the way toward development of targeted genetic treatments in the era of precision medicine.
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