Evidence map›Paper›PMID 31222445›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2020

Post-operative cerebellar mutism syndrome: rehabilitation issues.

Philippe F Paquier, Karin S Walsh, Kimberley M Docking, Helen Hartley, Ram Kumar, Coriene E Catsman-Berrevoets

Open access · hybridAbstract readReview
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. A case of postoperative cerebellar mutism with hyperphagia in a child following gross total resection of medulloblastoma occupying the cerebellar vermis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022
    Article
  15. Review
  16. Article
  17. Cerebellar mutism syndrome: From pathophysiology to rehabilitation.Frontiers in cell and developmental biology · 2022
    Review
  18. Mapping of long-term cognitive and motor deficits in pediatric cerebellar brain tumor survivors into a cerebellar white matter atlas.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  19. Communication-vulnerable pediatric patients following posterior fossa tumor surgery: the importance of augmentative and alternative communication.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  20. Augmentative and alternative communication in pCMS.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 5 countries.

Philippe F PaquierDepartment of Neuropsychology, University Hospital Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Karin S WalshDivision of Pediatric Neuropsychology, Children's National Health System, Departments of Pediatrics and Psychiatry, The George Washington University Medical Center, Washington DC, USA.
Kimberley M DockingDiscipline of Speech Pathology, University of Sydney, and Sydney Children's Hospital Network, Sydney, Australia.
Helen HartleyDepartment of Physiotherapy, Alder Hey Children's Hospital, Liverpool, UK.
Ram KumarDepartment of Paediatric Neurology, Alder Hey Children's Hospital, Liverpool, UK.
Coriene E Catsman-BerrevoetsDepartment of Pediatric Neurology, Erasmus University Hospital/ Sophia Children's Hospital, Postbox 2040, 3000 CA, Rotterdam, The Netherlands. c.catsman@erasmusmc.nl.
Alder Hey Children's Hospital · GBChildren's National · USErasmus MC - Sophia Children’s Hospital · NLSydney Children’s Hospitals Network · AUVrije Universiteit Brussel · BE

Funding

Research_ProjectU54HD090257 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VITTORIO GALLO, VITTORIO GALLO VITTORIO GALLO · 2016 to 2020
$5.9M
NICHD NIH HHS U54 HD090257
6 · The paper itself

Abstract

introductionTumors of the cerebellum are the most common brain tumors in children. Modern treatment and aggressive surgery have improved the overall survival. Consequently, growing numbers of survivors are at high risk for developing adverse and long-term neurological deficits including deficits of cognition, behavior, speech, and language. Post-operative cerebellar mutism syndrome (pCMS) is a well-known and frequently occurring complication of cerebellar tumor surgery in children. In the acute stage, children with pCMS may show deterioration of cerebellar motor function as well as pyramidal and cranial neuropathies. Most debilitating is the mutism or the severe reduction of speech and a range of neurobehavioral symptoms that may occur. In the long term, children that recover from pCMS continue to have more motor, behavioral, and cognitive problems than children who did not develop pCMS after cerebellar tumor surgery. The severity of these long-term sequelae seems to be related to the length of the mute phase. AIM OF THIS NARRATIVE REVIEW: The impact of pCMS on patients and families cannot be overstated. This contribution aims to discuss the present knowledge on the natural course, recovery, and rehabilitation of children with pCMS. We suggest future priorities in developing rehabilitation programs in order to improve the long-term quality of life and participation of children after cerebellar tumor surgery and after pCMS in particular.

Indexed as

Cerebellar DiseasesCerebellar NeoplasmsMutismCerebellumChildHumansPostoperative ComplicationsQuality of LifeAtaxiaBehaviorCerebellar mutism syndrome, brain tumorChildLanguageRehabilitationSpeech

Identifiers

PMID31222445
PMCPMC7250945
OpenAlexW2952579729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.