Evidence map›Paper›PMID 31222379›Full record

Trial reportEuropean journal of applied physiology2019

Cold-water immersion blunts and delays increases in circulating testosterone and cytokines post-resistance exercise.

Jacob E Earp, Disa L Hatfield, Andrew Sherman, Elaine C Lee, William J Kraemer

Open access · greenAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jacob E EarpDepartment of Kinesiology, University of Rhode Island, 25 West Independence Way, Kingston, RI, 02881, USA. Jacob_Earp@uri.edu.
Disa L HatfieldDepartment of Kinesiology, University of Rhode Island, 25 West Independence Way, Kingston, RI, 02881, USA.
Andrew ShermanDepartment of Kinesiology, University of Rhode Island, 25 West Independence Way, Kingston, RI, 02881, USA.
Elaine C LeeDepartment of Kinesiology, University of Connecticut, 2095 Hillside Road, U-1110, Storrs, CT, 06269, USA.
William J KraemerDepartment of Human Sciences, The Ohio State University, 305 Annie & John Glenn Ave, Columbus, OH, 43210, USA.
University of Rhode Island · USThe Ohio State University · USUniversity of Connecticut · US

Funding

University of Rhode Island Enhancement of Graduate Research Awards
6 · The paper itself

Abstract

introductionCold-water immersion (CWI) is often used to promote recovery by reducing exercise-induced muscle damage, soreness, and inflammation. However, recent reports have cautioned that CWI may attenuate the adaptive response to resistance training. PURPOSE: To determine the effect of post resistance-exercise CWI on circulating free testosterone (T) and cytokine (IL-6 and TNF-α) response.

methodsUsing a randomized and counterbalanced repeated-measures design, 11 resistance-trained men completed two workouts (6 sets of 10 repetitions of back squats at 80% of maximum load) a week apart after which they took part in either 15 min of CWI (15 °C) or passive recovery. T, IL-6, and TNFα were measured in blood samples taken before (PRE) and 5 (5POST), 15 (15POST), 30 (30POST), and 60 (60POST) min post-exercise and compared between treatments and over time.

resultsFor T, a significant interaction effect of condition over time (p = 0.030) as well as greater relative concentrations of T in CON (Δ9.2%) than CWI (Δ-0.5%, p = 0.049) at 30POST were observed. In addition, at 60POST, T dropped below PRE values in CWI (Δ-10.4%, p = 0.028) but not in CON (Δ-1.6%, p = 0.850). A suppressed cytokine response was observed after CWI in IL-6 at 30POST (CWI: Δ4.9%, CON: Δ47.5%, p = 0.041) and TNFα at 15POST (CWI: Δ5.3%, CON: Δ17.0%, p = 0.022).

conclusionsCWI blunted the T and cytokine response after a bout of resistance exercise. These results indicate that CWI results in an altered anabolic response and may help to explain the previous observation of attenuated hypertrophy when CWI is used after resistance exercise.

Indexed as

Cold TemperatureCytokinesHumansHypothermia, InducedImmersionMaleMyalgiaResistance TrainingTestosteroneWaterYoung AdultCytokinesTestosteroneWaterAnabolicCryotherapyHypertrophyIceInflammationRecovery

Identifiers

PMID31222379
OpenAlexW2950818808

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.