Evidence map›Paper›PMID 31222199›Full record

ArticleGigaScience2019

Accumulating computational resource usage of genomic data analysis workflow to optimize cloud computing instance selection.

Tazro Ohta, Tomoya Tanjo, Osamu Ogasawara

Abstract read
In one paragraph

Article in GigaScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tazro OhtaDatabase Center for Life Science, Joint Support-Center for Data Science Research, Research Organization of Information and Systems, Mishima, Shizuoka 411-8540, Japan.
Tomoya TanjoNational Institute of Informatics, Research Organization of Information and Systems, Tokyo 101-8430, Japan.
Osamu OgasawaraDNA Data Bank of Japan, National Institute of Genetics, Research Organization of Information and Systems, Mishima, Shizuoka 411-8540, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundContainer virtualization technologies such as Docker are popular in the bioinformatics domain because they improve the portability and reproducibility of software deployment. Along with software packaged in containers, the standardized workflow descriptors Common Workflow Language (CWL) enable data to be easily analyzed on multiple computing environments. These technologies accelerate the use of on-demand cloud computing platforms, which can be scaled according to the quantity of data. However, to optimize the time and budgetary restraints of cloud usage, users must select a suitable instance type that corresponds to the resource requirements of their workflows.

resultsWe developed CWL-metrics, a utility tool for cwltool (the reference implementation of CWL), to collect runtime metrics of Docker containers and workflow metadata to analyze workflow resource requirements. To demonstrate the use of this tool, we analyzed 7 transcriptome quantification workflows on 6 instance types. The results revealed that choice of instance type can deliver lower financial costs and faster execution times using the required amount of computational resources.

conclusionsCWL-metrics can generate a summary of resource requirements for workflow executions, which can help users to optimize their use of cloud computing by selecting appropriate instances. The runtime metrics data generated by CWL-metrics can also help users to share workflows between different workflow management frameworks.

Indexed as

Cloud ComputingSoftwareComputational BiologyGenomicsHigh-Throughput Nucleotide SequencingWorkflowcloud computingCommon Workflow Languagehigh-throughput nucleotide sequencing

Identifiers

PMID31222199
PMCPMC6479428

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.