ArticleScientific reports2019
The relationship between insecticide resistance, mosquito age and malaria prevalence in Anopheles gambiae s.l. from Guinea.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 89 citations in OpenAlex.
- Trial
- Modelling the impact of adopting new-generation insecticide-treated nets on malaria transmission and insecticide resistance.Parasites & vectors · 2026Article
- Multi-omics analysis identifies loci associated with pyrethroid resistance across sister species in the Anopheles gambiae species complex.BMC genomics · 2026Article
- Mechanisms of carbamate resistance in the malaria vector:Parasite epidemiology and control · 2026Review
- Genotype by environmental interactions shape insecticide resistance phenotypes in Culex pipiens and Culex restuans.Heredity · 2026Article
- Mosquito vector composition and biting behavior of malaria vectors in forest versus humid savanna eco-epidemiological settings of Cameroon.Malaria journal · 2026Article
- Spatial and temporal signatures of genomic insecticide resistance in the Anopheles arabiensis mosquito malaria vector from Ethiopia.Research square · 2026Article
- Phytol from Sphaeranthus indicus: A Natural Insecticide Against Aedes aegypti and Culex quinquefasciatus.Acta parasitologica · 2026Article
- Novel insecticide resistance mutations associated with variable PBO synergy in Anopheles gambiae s.l. from the Democratic Republic of Congo.Scientific reports · 2025Article
- Determining mosquito age using surface-enhanced Raman spectroscopy and artificial neural networks: insights into the influence of origin and sex.Parasites & vectors · 2025Article
- Daytime and public space exposure to Anopheles funestus bites in Western Province, Zambia: implications for malaria surveillance and control.Malaria journal · 2025Article
- Omics Approaches in Understanding Insecticide Resistance in Mosquito Vectors.International journal of molecular sciences · 2025Review
- Genetic markers associated with the widespread insecticide resistance in malaria vector Anopheles funestus populations across Tanzania.Parasites & vectors · 2024Article
- Impact of insecticide resistance on malaria vector competence: a literature review.Malaria journal · 2023Review
- Article
- Relationships between biological age, distance from aquatic habitats and pyrethroid resistance status of Anopheles funestus mosquitoes in south-eastern Tanzania.Malaria journal · 2022Article
- Omitting age-dependent mosquito mortality in malaria models underestimates the effectiveness of insecticide-treated nets.PLoS computational biology · 2022Article
- Effects of agricultural pesticides on the susceptibility and fitness of malaria vectors in rural south-eastern Tanzania.Parasites & vectors · 2022Article
- Association of Reduced Long-Lasting Insecticidal Net Efficacy and Pyrethroid Insecticide Resistance With Overexpression of CYP6P4, CYP6P3, and CYP6Z1 in Populations of Anopheles coluzzii From Southeast Côte d'Ivoire.The Journal of infectious diseases · 2022Article
- Review
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Authors and funding
10 authors at 2 institutions in 3 countries.
Funding
Abstract
Insecticide resistance across sub-Saharan Africa may impact the continued effectiveness of malaria vector control. We investigated the association between carbamate and pyrethroid resistance with Anopheles gambiae s.l. parity, Plasmodium falciparum infection, and molecular insecticide resistance mechanisms in Guinea. Pyrethroid resistance was intense, with field populations surviving ten times the insecticidal concentration required to kill susceptible individuals. The L1014F kdr-N1575Y haplotype and I1527T mutation were significantly associated with mosquito survival following permethrin exposure (Prevalence Ratio; PR = 1.92, CI = 1.09-3.37 and PR = 2.80, CI = 1.03-7.64, respectively). Partial restoration of pyrethroid susceptibility following synergist pre-exposure suggests a role for mixed-function oxidases. Carbamate resistance was lower and significantly associated with the G119S Ace-1 mutation. Oocyst rates were 6.8% and 4.2% among resistant and susceptible mosquitoes, respectively; survivors of bendiocarb exposure were significantly more likely to be infected. Pyrethroid resistant mosquitoes had significantly lower parity rates than their susceptible counterparts (PR = 1.15, CI = 1.10-1.21). Our findings emphasize the need for additional studies directly assessing the influence of insecticide resistance on mosquito fitness.
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