ArticleScientific reports2019
EEG functional connectivity metrics wPLI and wSMI account for distinct types of brain functional interactions.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.
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Who cites it
72 citing papers in PubMed, 1 synthesis or guideline pooled it.
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- Dissociable effects of β-tACS on spectral power and network organization for proximal versus distal upper-limb recovery in subacute stroke: double-blind, randomized, sham-controlled trial with high-density EEG.Journal of neuroengineering and rehabilitation · 2026Trial
- EEG functional connectivity measures for differentiating 6-month consciousness-related outcome after brain injury.BMC medical imaging · 2026Article
- Reduced information sharing within the orienting network predicts intelligence in late childhood.Developmental cognitive neuroscience · 2026Article
- Chiropractic Care Is Associated with Frequency-Specific Reorganisation of Triple-Network Brain Dynamics: A Source-Localised EEG Study.Brain sciences · 2026Article
- Electrophysiological Changes in Resting-State EEG Following REAC BWO-G_B Neurobiological Modulation in Healthy Adults: A Spectral and Multivariate Exploratory Study.Brain sciences · 2026Article
- The electrophysiological basis of resting-state fMRI hyperconnectivity in early Alzheimer's disease.Alzheimer's research & therapy · 2026Article
- Mechanisms of acupuncture-regulated cortical plasticity after stroke based on TMS-EEG-MEP integration.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- EEG based multifunctional connectivity fusion across frequency bands and parameters promote motor function assessment in stroke: a pilot study.Journal of neuroengineering and rehabilitation · 2026Article
- Functional connectivity in electroencephalography of brain tumor patients in status epilepticus: a retrospective evaluation of prognostic value.Quantitative imaging in medicine and surgery · 2026Article
- Post-stroke dysphagia is associated with abnormal gamma power and phase synchronisation during swallowing.Frontiers in human neuroscience · 2026Article
- From Brain Networks to Sleep Perception: EEG-Derived Global Efficiency is Associated with Subjective Sleep Quality in University Students.Nature and science of sleep · 2026Article
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- Disrupted Global Brain Dynamics in Adolescents With Comorbid Anxiety and Depression: Neural Mechanisms and Classification Based on EEG Microstates.Depression and anxiety · 2026Article
- Behavioral, experiential, and physiological signatures of mind blanking.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- EEG analysis of brain dynamics in a simulated multi-task and multi-stage learning environment.NPJ science of learning · 2025Article
- Article
- Odorant representations indicate nonlinear processing across the olfactory system.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Linking the multiple-demand cognitive control system to human electrophysiological activity.Neuropsychologia · 2025Review
12 more citing papers are in PubMed but not listed here.
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Abstract
The weighted Phase Lag Index (wPLI) and the weighted Symbolic Mutual Information (wSMI) represent two robust and widely used methods for MEG/EEG functional connectivity estimation. Interestingly, both methods have been shown to detect relative alterations of brain functional connectivity in conditions associated with changes in the level of consciousness, such as following severe brain injury or under anaesthesia. Despite these promising findings, it was unclear whether wPLI and wSMI may account for distinct or similar types of functional interactions. Using simulated high-density (hd-)EEG data, we demonstrate that, while wPLI has high sensitivity for couplings presenting a mixture of linear and nonlinear interdependencies, only wSMI can detect purely nonlinear interaction dynamics. Moreover, we evaluated the potential impact of these differences on real experimental data by computing wPLI and wSMI connectivity in hd-EEG recordings of 12 healthy adults during wakefulness and deep (N3-)sleep, characterised by different levels of consciousness. In line with the simulation-based findings, this analysis revealed that both methods have different sensitivity for changes in brain connectivity across the two vigilance states. Our results indicate that the conjoint use of wPLI and wSMI may represent a powerful tool to study the functional bases of consciousness in physiological and pathological conditions.
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