Evidence map›Paper›PMID 31222008›Full record

ArticleScientific reports2019

High-density Mapping Guided Pulmonary Vein Isolation for Treatment of Atrial Fibrillation - Two-year clinical outcome of a single center experience.

J Siebermair, B Neumann, F Risch, L Riesinger, N Vonderlin, M Koehler, K Lackermaier, S Fichtner, K Rizas, S M Sattler and 4 more

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Mapping strategies and ablation of premature atrial complexes.Herzschrittmachertherapie & Elektrophysiologie · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

J SiebermairDepartment of Cardiology and Vascular Medicine, West-German Heart and Vascular Center, University Duisburg-Essen, Essen, Germany.
B NeumannDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany.
F RischDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany.
L RiesingerDepartment of Cardiology and Vascular Medicine, West-German Heart and Vascular Center, University Duisburg-Essen, Essen, Germany.
N VonderlinDepartment of Cardiology and Vascular Medicine, West-German Heart and Vascular Center, University Duisburg-Essen, Essen, Germany.
M KoehlerDepartment of Cardiology and Vascular Medicine, West-German Heart and Vascular Center, University Duisburg-Essen, Essen, Germany.
K LackermaierDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany.
S FichtnerDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany.
K RizasDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany.
S M SattlerDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany.ORCID http://orcid.org/0000-0003-3558-8329
M F SinnerDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany.
S KääbDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany.
H L EstnerDepartment of Medicine I, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany.
R WakiliDepartment of Cardiology and Vascular Medicine, West-German Heart and Vascular Center, University Duisburg-Essen, Essen, Germany. reza.wakili@uk-essen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary vein isolation (PVI) as interventional treatment for atrial fibrillation (AF) aims to eliminate arrhythmogenic triggers from the PVs. Improved signal detection facilitating a more robust electrical isolation might be associated with a better outcome. This retrospective cohort study compared PVI procedures using a novel high-density mapping system (HDM) with improved signal detection vs. age- and sex-matched PVIs using a conventional 3D mapping system (COM). Endpoints comprised freedom from AF and procedural parameters. In total, 108 patients (mean age 63.9 ± 11.2 years, 56.5% male, 50.9% paroxysmal AF) were included (n = 54 patients/group). Our analysis revealed that HDM was not superior regarding freedom from AF (mean follow-up of 494.7 ± 26.2 days), with one- and two-year AF recurrence rates of 38.9%/46.5% (HDM) and 38.9%/42.2% (COM), respectively. HDM was associated with reduction in fluoroscopy times (18.8 ± 10.6 vs. 29.8 ± 13.4 min; p < 0.01) and total radiation dose (866.0 ± 1003.3 vs. 1731.2 ± 1978.4 cGy; p < 0.01) compared to the COM group. HDM was equivalent but not superior to COM with respect to clinical outcome after PVI and resulted in reduced fluoroscopy time and radiation exposure. These results suggest that HDM-guided PVI is effective and safe for AF ablation. Potential benefits in comparison to conventional mapping systems, e.g. arrhythmia recurrence rates, have to be addressed in randomized trials.

Indexed as

AgedAtrial FibrillationCatheter AblationEpicardial MappingFemaleFluoroscopyHumansMaleMiddle AgedPulmonary VeinsRadiation ExposureRecurrenceRetrospective StudiesTreatment Outcome

Identifiers

PMID31222008
PMCPMC6586935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.