Evidence map›Paper›PMID 31221898›Full record

Observational studyPediatrics2019

Cervical Spine Injury Risk Factors in Children With Blunt Trauma.

Julie C Leonard, Lorin R Browne, Fahd A Ahmad, Hamilton Schwartz, Michael Wallendorf, Jeffrey R Leonard, E Brooke Lerner, Nathan Kuppermann

Open access · bronzeAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Mechanism of injury and special considerations as predictive of serious injury: A systematic review.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2022
    Pooled it
  3. Article
  4. Observational
  5. Observational
  6. Fast Interpretable Greedy-Tree Sums.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Observational
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Julie C LeonardDepartments of Pediatrics and julie.leonard@nationwidechildrens.org.
Lorin R BrowneDepartment of Pediatrics and Emergency Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Fahd A AhmadDepartments of Pediatrics and.
Hamilton SchwartzDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center and College of Medicine, University of Cincinnati, Cincinnati, Ohio; and.
Michael WallendorfBiostatistics, School of Medicine, Washington University, St Louis, Missouri.
Jeffrey R LeonardNeurosurgery, Nationwide Children's Hospital and College of Medicine, The Ohio State University, Columbus, Ohio.
E Brooke LernerDepartment of Pediatrics and Emergency Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
Nathan KuppermannDepartments of Emergency Medicine and Pediatrics, School of Medicine, University of California, Davis, Sacramento, California.
Medical College of Wisconsin · USNationwide Children's Hospital · USCincinnati Children's Hospital Medical Center · USUniversity of California, Davis · USWashington University in St. Louis · US

Funding

PILOT STUDY TO DEVELOP A PEDIATRIC CERVICAL SPINE INJURY RISK ASSESSMENT TOOLR21HD076108 · NICHD · WASHINGTON UNIVERSITY · PI LEONARD, JULIE C. · 2013 to 2014
$420k
NICHD NIH HHS R21 HD076108
6 · The paper itself

Abstract

backgroundAdult prediction rules for cervical spine injury (CSI) exist; however, pediatric rules do not. Our objectives were to determine test accuracies of retrospectively identified CSI risk factors in a prospective pediatric cohort and compare them to a de novo risk model.

methodsWe conducted a 4-center, prospective observational study of children 0 to 17 years old who experienced blunt trauma and underwent emergency medical services scene response, trauma evaluation, and/or cervical imaging. Emergency department providers recorded CSI risk factors. CSIs were classified by reviewing imaging, consultations, and/or telephone follow-up. We calculated bivariable relative risks, multivariable odds ratios, and test characteristics for the retrospective risk model and a de novo model.

resultsOf 4091 enrolled children, 74 (1.8%) had CSIs. Fourteen factors had bivariable associations with CSIs: diving, axial load, clotheslining, loss of consciousness, neck pain, inability to move neck, altered mental status, signs of basilar skull fracture, torso injury, thoracic injury, intubation, respiratory distress, decreased oxygen saturation, and neurologic deficits. The retrospective model (high-risk motor vehicle crash, diving, predisposing condition, neck pain, decreased neck mobility (report or exam), altered mental status, neurologic deficits, or torso injury) was 90.5% (95% confidence interval: 83.9%-97.2%) sensitive and 45.6% (44.0%-47.1%) specific for CSIs. The de novo model (diving, axial load, neck pain, inability to move neck, altered mental status, intubation, or respiratory distress) was 92.0% (85.7%-98.1%) sensitive and 50.3% (48.7%-51.8%) specific.

conclusionsOur findings support previously identified pediatric CSI risk factors and prospective pediatric CSI prediction rule development.

Indexed as

Clinical Decision RulesAdolescentCervical VertebraeChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleNeck InjuriesProspective StudiesRetrospective StudiesRisk FactorsWounds, Nonpenetrating

Identifiers

PMID31221898
PMCPMC6615532
OpenAlexW2952235003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.