Evidence map›Paper›PMID 31221887›Full record

ArticleBMJ open2019

Effectiveness of interventions for dementia in low- and middle-income countries: protocol for a systematic review, pairwise and network meta-analysis.

Maximilian Salcher-Konrad, Huseyin Naci, David McDaid, Suvarna Alladi, Deborah Oliveira, Andra Fry, Shereen Hussein, Martin Knapp, Christine Wayua Musyimi, David Musyimi Ndetei and 2 more

Abstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maximilian Salcher-KonradPersonal Social Services Research Unit (PSSRU), London School of Economics and Political Science, London, UK.ORCID 0000-0002-5628-5266
Huseyin NaciDepartment of Health Policy, London School of Economics and Political Science, London, UK.ORCID 0000-0002-7192-5751
David McDaidPersonal Social Services Research Unit (PSSRU), London School of Economics and Political Science, London, UK.
Suvarna AlladiNIMHANS, Bangalore, India.
Deborah OliveiraFederal University of Sao Paulo (UNIFESP), Sao Paulo, Brazil.
Andra FryLibrary, London School of Economics and Political Science, London, UK.
Shereen HusseinPersonal Social Services Research Unit (PSSRU), University of Kent, Canterbury, UK.ORCID 0000-0002-7946-0717
Martin KnappPersonal Social Services Research Unit (PSSRU), London School of Economics and Political Science, London, UK.
Christine Wayua MusyimiAfrica Mental Health Foundation, Nairobi, Kenya.
David Musyimi NdeteiAfrica Mental Health Foundation, Nairobi, Kenya.ORCID 0000-0001-6891-4990
Mariana Lopez-OrtegaNational Institute of Geriatrics, National Institutes of Health, Mexico City, Mexico.
Adelina Comas-HerreraPersonal Social Services Research Unit (PSSRU), London School of Economics and Political Science, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere are more people living with dementia in low- and middle-income countries (LMICs) than in high-income countries. Evidence-based interventions to improve the lives of people living with dementia and their carers are needed, but a systematic mapping of methodologically robust studies in LMICs and synthesis of the effectiveness of dementia interventions in these settings is missing. METHODS AND ANALYSIS: A systematic review and meta-analysis will be conducted to answer the question: Which dementia interventions were shown to be effective in LMICs and how do they compare to each other? Electronic database searches (MEDLINE, EMBASE, PsycINFO, CINAHL Plus, Global Health, WHO Global Index Medicus, Virtual Health Library, Cochrane CENTRAL, Social Care Online, BASE, MODEM Toolkit, Cochrane Database of Systematic Reviews) will be complemented by hand searching of reference lists and local knowledge of existing studies from an international network of researchers in dementia from LMICs. Studies will be eligible for inclusion if they were published between 2008 and 2018, conducted in LMICs and evaluated the effectiveness of a dementia intervention using a study design that supports causal inference of the treatment effect. We will include both randomised and non-randomised studies due to an anticipated low number of well-conducted randomised trials in LMICs and potentially greater external validity of non-randomised studies conducted in routine care settings. In addition to narrative synthesis of the interventions, feasibility of pairwise and network meta-analyses will be explored to obtain pooled effects of relative treatment effects. ETHICS AND DISSEMINATION: Secondary analysis of published studies, therefore no ethics approval required. Planned dissemination channels include a peer-reviewed publication as well as a website, DVD and evidence summaries. PROSPERO REGISTRATION NUMBER: CRD42018106206.

Indexed as

AdolescentAdultAgedAlzheimer DiseaseDementiaDeveloping CountriesHumansIncomeMiddle AgedNetwork Meta-Analysis as TopicResearch DesignSystematic Reviews as TopicTreatment OutcomeYoung AdultAlzheimer diseasedementiadeveloping countrieslamicslow and middle income countriessystematic review

Identifiers

PMID31221887
PMCPMC6588974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.