Evidence map›Paper›PMID 31221858›Full record

ArticleScience (New York, N.Y.)2019

Eduard Ansaldo, Leianna C Slayden, Krystal L Ching, Meghan A Koch, Natalie K Wolf, Damian R Plichta, Eric M Brown, Daniel B Graham, Ramnik J Xavier, James J Moon and 1 more

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 345 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
345citing papers in PubMed, 4 pooled it
20.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

345 citing papers in PubMed, 4 syntheses or guidelines pooled it, 532 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Vancomycin Protects Against Lung Injury and Promotes Butyrate Metabolism.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  17. Review
  18. Fasting primes small intestinal regeneration after damage via a microbiome-metabolite-chromatin axis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  19. Article
  20. Article

285 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Eduard AnsaldoDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID 0000-0002-7128-3373
Leianna C SlaydenDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID 0000-0003-0231-0961
Krystal L ChingDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID 0000-0002-1181-0119
Meghan A KochDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.ORCID 0000-0002-9539-4027
Natalie K WolfDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.
Damian R PlichtaBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-6555-2557
Eric M BrownBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0001-8415-8021
Daniel B GrahamBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Ramnik J XavierBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0002-5630-5167
James J MoonCenter for Immunology and Inflammatory Diseases and Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-8246-931X
Gregory M BartonDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA. barton@berkeley.edu.ORCID 0000-0002-3793-0100
University of California, Berkeley · USBroad Institute · USMassachusetts General Hospital · US

Funding

The role of Listeria cyclic-di-AMP during infection and immunityP01AI063302 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI STANLEY, SARAH A · 2004 to 2025
$45.5M
THE MOLECULAR BASIS OF CELL FUNCTIONT32GM007232 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID, UNAL, ELCIN · 1985 to 2022
$36.4M
Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3M
The influence of maternal antibodies on neonatal intestinal immunityR01AI142926 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI BARTON, GREGORY M · 2018 to 2020
$1.1M
CD4+ T cell Tolerance to Enteric Commensal BacteriaR21AI124143 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MOON, JAMES J · 2017 to 2018
$448k
NIAID NIH HHS P01 AI063302NIAID NIH HHS R01 AI142926NIAID NIH HHS R21 AI124143NIDDK NIH HHS P30 DK043351NIGMS NIH HHS T32 GM007232Wellcome Trust
6 · The paper itself

Abstract

Intestinal adaptive immune responses influence host health, yet only a few intestinal bacteria species that induce cognate adaptive immune responses during homeostasis have been identified. Here, we show that

Indexed as

Adaptive ImmunityHomeostasisAnimalsCell MovementFemaleGastrointestinal MicrobiomeGerm-Free LifeImmunity, MucosalImmunoglobulin GIntestinal MucosaIntestinesMaleMiceMice, Inbred C57BLT-Lymphocytes, Helper-InducerVerrucomicrobiaImmunoglobulin G

Identifiers

PMID31221858
PMCPMC6645389
OpenAlexW2952093130

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.