Evidence map›Paper›PMID 31221785›Full record

ArticleHaematologica2019

Chimeric antigen receptor T-cell therapy for acute myeloid leukemia: how close to reality?

Katherine D Cummins, Saar Gill

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Significant Advancements and Evolutions in Chimeric Antigen Receptor Design.International journal of molecular sciences · 2024
    Review
  7. Increased expression of CD70 in relapsed acute myeloid leukemia after hypomethylating agents.Virchows Archiv : an international journal of pathology · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Katherine D CumminsDivision of Hematology-Oncology and Center for Cellular Immunotherapies, University of Pennsylvania, PA, USA.
Saar GillDivision of Hematology-Oncology and Center for Cellular Immunotherapies, University of Pennsylvania, PA, USA saargill@pennmedicine.upenn.
University of Pennsylvania · US

Funding

Project 3: Combinatorial and gene-editing approaches to enhance the efficacy of CAR T cell therapy of multiple myeloma.P01CA214278 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CARL H. JUNE · 2017 to 2026
$26.8M
NCI NIH HHS P01 CA214278
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell- and Tissue-Based TherapyHumansImmunotherapyLeukemia, Myeloid, AcutePrognosisReceptors, Antigen, T-CellReceptors, Chimeric AntigenReceptors, Antigen, T-CellReceptors, Chimeric Antigen

Identifiers

PMID31221785
PMCPMC6601074
OpenAlexW2952168835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.