Evidence map›Paper›PMID 31221734›Full record

ArticlePlant physiology2019

A Neighboring Aromatic-Aromatic Amino Acid Combination Governs Activity Divergence between Tomato Phytoene Synthases.

Hongbo Cao, Hongmei Luo, Hui Yuan, Mohamed A Eissa, Theodore W Thannhauser, Ralf Welsch, Yu-Jin Hao, Lailiang Cheng, Li Li

Abstract read
In one paragraph

Article in Plant physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Cia Zeaxanthin Biosynthesis,International journal of molecular sciences · 2022
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  19. Down-regulation ofFrontiers in plant science · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hongbo CaoRobert W. Holley Center for Agriculture and Health, United States Department of Agriculture-Agricultural Research Service, Cornell University, Ithaca, New York 14853.
Hongmei LuoPlant Breeding and Genetics Section, School of Integrative Plant Science, Cornell University, Ithaca, New York 14853.
Hui YuanRobert W. Holley Center for Agriculture and Health, United States Department of Agriculture-Agricultural Research Service, Cornell University, Ithaca, New York 14853.ORCID 0000-0002-8309-6276
Mohamed A EissaPlant Breeding and Genetics Section, School of Integrative Plant Science, Cornell University, Ithaca, New York 14853.
Theodore W ThannhauserRobert W. Holley Center for Agriculture and Health, United States Department of Agriculture-Agricultural Research Service, Cornell University, Ithaca, New York 14853.
Ralf WelschUniversity of Freiburg, Faculty of Biology II, 79104 Freiburg, Germany.ORCID 0000-0002-2865-2743
Yu-Jin HaoState Key Laboratory of Crop Biology, National Research Center for Apple Engineering and Technology, Shandong Agricultural University, Tai'an, Shandong 271018, China.ORCID 0000-0001-7258-3792
Lailiang ChengHorticulture Section, School of Integrative Plant Science, Cornell University, Ithaca, New York 14853.ORCID 0000-0003-1759-9761
Li LiRobert W. Holley Center for Agriculture and Health, United States Department of Agriculture-Agricultural Research Service, Cornell University, Ithaca, New York 14853 ll37@cornell.edu.ORCID 0000-0002-4352-4061

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carotenoids exert multifaceted roles to plants and are critically important to humans. Phytoene synthase (PSY) is a major rate-limiting enzyme in the carotenoid biosynthetic pathway. PSY in plants is normally found as a small enzyme family with up to three members. However, knowledge of PSY isoforms in relation to their respective enzyme activities and amino acid residues that are important for PSY activity is limited. In this study, we focused on two tomato (

Indexed as

FruitGene Expression Regulation, PlantGeranylgeranyl-Diphosphate GeranylgeranyltransferasePlant ProteinsSolanum lycopersicumSolanum tuberosumGeranylgeranyl-Diphosphate GeranylgeranyltransferasePlant Proteins

Identifiers

PMID31221734
PMCPMC6670109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.