Evidence map›Paper›PMID 31221727›Full record

ArticleJournal of cell science2019

Anterior-enriched filopodia create the appearance of asymmetric membrane microdomains in polarizing

Nisha Hirani, Rukshala Illukkumbura, Tom Bland, Grégoire Mathonnet, Delphine Suhner, Anne-Cecile Reymann, Nathan W Goehring

Abstract read
In one paragraph

Article in Journal of cell science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Asymmetric distribution of actin-related proteins in the earlybioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Wnt Signaling Induces Asymmetric Dynamics in the Actomyosin Cortex of theFrontiers in cell and developmental biology · 2021
    Article
  13. Roles of Actin in the Morphogenesis of the EarlyInternational journal of molecular sciences · 2020
    Review
  14. Mechanochemical Control of Symmetry Breaking in theFrontiers in cell and developmental biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nisha HiraniThe Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
Rukshala IllukkumburaThe Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.ORCID 0000-0002-2131-678X
Tom BlandThe Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
Grégoire MathonnetInstitut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique, UMR7104, Institut National de la Santé et de la Recherche Médicale, U1258, and Université de Strasbourg, 67404 Illkirch, France.
Delphine SuhnerInstitut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique, UMR7104, Institut National de la Santé et de la Recherche Médicale, U1258, and Université de Strasbourg, 67404 Illkirch, France.
Anne-Cecile ReymannInstitut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique, UMR7104, Institut National de la Santé et de la Recherche Médicale, U1258, and Université de Strasbourg, 67404 Illkirch, France.ORCID 0000-0002-0517-5083
Nathan W GoehringThe Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK nate.goehring@crick.ac.uk.ORCID 0000-0001-8710-4467

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Medical Research Council FC001086NIH HHS P40 OD010440Wellcome Trust FC001086
6 · The paper itself

Abstract

The association of molecules within membrane microdomains is critical for the intracellular organization of cells. During polarization of the

Indexed as

ActinsAnimalsCaenorhabditis elegansEmbryo, NonmammalianGreen Fluorescent ProteinsMembrane MicrodomainsPseudopodiaZygoteActinsGreen Fluorescent ProteinsC. elegansCell cortexCell polarityFilopodiaPAR proteinsPIP2

Identifiers

PMID31221727
PMCPMC6679585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.