Evidence map›Paper›PMID 31221145›Full record

ArticleMalaria journal2019

Prospects and strategies for malaria elimination in the Greater Mekong Sub-region: a qualitative study.

Nils Kaehler, Bipin Adhikari, Phaik Yeong Cheah, Lorenz von Seidlein, Nicholas P J Day, Daniel H Paris, Marcel Tanner, Christopher Pell

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

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  12. Different In Vitro Drug Susceptibility Profile ofTropical medicine and infectious disease · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Nils KaehlerSwiss Tropical and Public Health Institute, Basel, Switzerland. dr.nils.kaehler@gmail.com.ORCID http://orcid.org/0000-0002-0555-0242
Bipin AdhikariMahidol Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Phaik Yeong CheahMahidol Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Lorenz von SeidleinMahidol Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Nicholas P J DayMahidol Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Daniel H ParisSwiss Tropical and Public Health Institute, Basel, Switzerland.
Marcel TannerSwiss Tropical and Public Health Institute, Basel, Switzerland.
Christopher PellAmsterdam Institute for Global Health and Development (AIGHD), Amsterdam, The Netherlands.
Mahidol University · THSwiss Tropical and Public Health Institute · CHAmsterdam Institute for Global Health and Development · NL

Funding

Wellcome TrustWellcome Trust 101148/Z/13/Z
6 · The paper itself

Abstract

backgroundAs malaria elimination becomes a goal in malaria-endemic nations, questions of feasibility become critical. This article explores the potential challenges associated with this goal and future strategies for malaria elimination in the Greater Mekong Sub-region.

methodsThirty-two semi-structured interviews were conducted with policy makers (n = 17) and principal investigators (n = 15) selected based on their involvement in malaria prevention, control and elimination in the GMS. Interviews were audio-recorded and transcribed for qualitative content (thematic) analysis using QSR NVivo.

resultsAll respondents described current malaria control and elimination strategies, such as case detection and management, prevention and strengthening of surveillance systems as critical and of equal priority. Aware of the emergence of multi-drug resistance in the GMS, researchers and policy makers outlined the need for additional elimination tools. As opposed to a centralized strategy, more targeted and tailored approaches to elimination were recommended. These included targeting endemic areas, consideration for local epidemiology and malaria species, and strengthening the peripheral health system. A decline in malaria transmission could lead to complacency amongst funders and policy makers resulting in a reduction or discontinuation of support for malaria elimination. Strong commitment of policymakers combined with strict monitoring and supervision by funders were considered pivotal to successful elimination programmes.

conclusionAgainst a backdrop of increasing anti-malarial resistance and decreasing choices of anti-malarial regimens, policy makers and researchers stressed the urgency of finding new malaria elimination strategies. There was consensus that multi-pronged strategies and approaches are needed, that no single potential tool/strategy can be appropriate to all settings. Hence there is a need to customize malaria control and elimination strategies based on the better surveillance data.

Indexed as

Drug Resistance, MultipleAdministrative PersonnelAntimalarialsAsia, SoutheasternDisease EradicationHumansMalariaQualitative ResearchSurveys and QuestionnairesAntimalarialsElimination strategiesGovernanceHealth systemsMalaria controlMalaria eliminationPolicySurveillance and responseTargeted approach

Identifiers

PMID31221145
PMCPMC6585139
OpenAlexW2952618401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.