ArticleBMC musculoskeletal disorders2019
Development of 3D method to assess intramuscular spatial distribution of fat infiltration in patients with rotator cuff tear: reliability and concurrent validity.
Article in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- MRI-based rotator cuff muscle morphometry across isolated supraspinatus tendon tear severity.Skeletal radiology · 2026Article
- Fatty infiltration of the gluteus medius and minimus muscles: volumetric analysis of both hips in patients with unilateral greater trochanteric pain syndrome using 2-point-Dixon MRI.Insights into imaging · 2025Article
- Advances in Shoulder Pain Imaging: A Narrative Review of Current Practice and Emerging Trends.Current medical imaging · 2025Article
- Developing a three-dimensional convolutional neural network for automated full-volume multi-tissue segmentation of the shoulder with comparisons to Goutallier classification and partial volume muscle quality analysis.Journal of shoulder and elbow surgery · 2025Article
- Systematic identification of aberrant non-coding RNAs and their mediated modules in rotator cuff tears.Frontiers in molecular biosciences · 2022Article
- Fatty degeneration of the rotator cuff: pathogenesis, clinical implications, and future treatment.JSES reviews, reports, and techniques · 2021Article
- Ultrasound shear wave elastography and its association with rotator cuff tear characteristics.JSES international · 2021Article
- Rotator cuff tear degeneration and the role of fibro-adipogenic progenitors.Annals of the New York Academy of Sciences · 2021Review
- New insights into intrinsic foot muscle morphology and composition using ultra-high-field (7-Tesla) magnetic resonance imaging.BMC musculoskeletal disorders · 2021Article
- Foot exercise plus education versus wait and see for the treatment of plantar heel pain (FEET trial): a protocol for a feasibility study.Journal of foot and ankle research · 2020Article
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Abstract
backgroundIntramuscular fat infiltration is a critical factor in surgical decision-making and is the most important factor used to prognosticate surgical repair outcomes in patients with rotator cuff tears. Quantitative 3D assessment of total rotator cuff fat infiltration in patients with rotator cuff tears has been realized. However, a reproducible method to evaluate 3D spatial distribution of rotator cuff intramuscular fat has not been established. The objective of this study was to establish the reproducibility, change detectable beyond error, and concurrent validity of a semi-automated method to evaluate the 3D spatial distribution of fat infiltration and muscle volume in patients with rotator cuff tears.
methodsThirteen consecutive patients diagnosed with symptomatic rotator cuff pathology and 3.0 T MRI confirmation at a single center were included. Fat-water imaging was used to quantify 3D intramuscular fat (%fat) in sagittal oblique sequences and intramuscular spatial distribution with the semi-automated technique. Each rotator cuff muscle was manually segmented yielding %fat in four axial intramuscular quartile-regions (superior-inferior; Q1-4) and three sagittal (medial/ intermediate/ lateral) regions. Reliability and concurrent validity of %fat and whole muscle volume were calculated with intraclass correlation coefficients (ICC).
resultsIntra-rater reliability for intramuscular sagittal divisions (ICC = 0.93-0.99) and axial divisions (ICC = 0.78-0.99) was good/excellent. Inter-rater reliability for %fat (ICC = 0.82-0.99) and volume (ICC = 0.92-0.99) was good/excellent. Concurrent validity with commercialized software showed good/excellent agreement (ICC = 0.66-0.99).
conclusionsA new semi-automated method to assess 3-dimensional intramuscular distribution of fat infiltration in patients with rotator cuff tears using advanced MR imaging demonstrates high intra and inter-rater reliability and good concurrent validity. Minimal detectable change thresholds established facilitate clinical interpretation for future clinical application of this technique to assess change and treatment efficacy in patients with rotator cuff tears.
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