Evidence map›Paper›PMID 31221010›Full record

ArticleClinical linguistics & phonetics2019

Speech and motor speech disorders and intelligibility in adolescents with Down syndrome.

Erin M Wilson, Leonard Abbeduto, Stephen M Camarata, Lawrence D Shriberg

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Clinical linguistics & phonetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05016037 (Predictors of Speech Ability in Down Syndrome), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05016037 nacompletednot on this mapstarted 2022, after this paper: background citation

Predictors of Speech Ability in Down Syndrome

TypeinterventionalSponsorVanderbilt University Medical CenterRan2022 to 2025Enrolled18ConditionsSpeech Intelligibility Intervention in Down SyndromeArmsLexically based speech recast
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. Community-Supported Shared Infrastructure in Support of Speech Accessibility.Journal of speech, language, and hearing research : JSLHR · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Prosodic Development During the Early School-Age Years.Journal of speech, language, and hearing research : JSLHR · 2022
    Article
  13. Article
  14. Evaluating Verbal Fluency Outcome Measures in Children With Down Syndrome.American journal on intellectual and developmental disabilities · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Erin M Wilsona Speech and Feeding Disorders Laboratory , MGH Institute of Health Professions , Boston , MA , USA.
Leonard Abbedutob MIND Institute and Department of Psychiatry and Behavioral Sciences , School of Medicine, University of California , Davis , CA , USA.
Stephen M Camaratac Department of Hearing and Speech Sciences , Vanderbilt University , Nashville , TN , USA.
Lawrence D Shribergd Intellectual and Developmental Disabilities Research Center, Waisman Center , University of Wisconsin-Madison , Madison , WI , USA.
MGH Institute of Health Professions · USUniversity of California, Davis · USUniversity of Wisconsin–Madison · USVanderbilt University · US

Funding

STUDIES IN DEVELOPMENTAL PHONOLOGICAL DISORDERSR01DC000496 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI SHRIBERG, LAWRENCE D · 1988 to 2017
$9.9M
LINGUISTIC COMMUNICATION AND MENTAL RETARDATIONR01HD024356 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI ABBEDUTO, LEONARD J. · 1987 to 2022
$9.0M
Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI MESSING, ALBEE · 2016 to 2020
$6.0M
SPEECH MOVEMENT CLASSIFICATION FOR ASSESSING AND TREATING ALSR01DC013547 · NIDCD · MGH INSTITUTE OF HEALTH PROFESSIONS · PI GREEN, JORDAN R · 2014 to 2018
$3.2M
NICHD NIH HHS R01 HD024356NICHD NIH HHS U54 HD090256NIDCD NIH HHS R01 DC000496NIDCD NIH HHS R01 DC013547
6 · The paper itself

Abstract

The goal of this research was to assess the support for motor speech disorders as explanatory constructs to guide research and treatment of reduced intelligibility in persons with Down syndrome (DS). Participants were the 45 adolescents with DS in the prior paper who were classified into five mutually-exclusive motor speech classifications using the Speech Disorders Classification System. An ordinal index classified participants' percentage of intelligible words in conversation as High (≥ 85%), Moderate (80% - 84.9%), or Low (< 80%). Statistical analyses tested for significant differences in intelligibility status associated with demographic, intelligence, and language variables, and intelligibility status associated with motor speech classifications and speech, prosody, and voice variables. For the 10 participants who met criteria for concurrent Childhood Dysarthria and Childhood Apraxia of Speech at assessment, 80% had reduced (Moderate or Low) intelligibility and 20% had High intelligibility (significant effect size: 0.644). Proportionally more of the 32 participants who met criteria for either dysarthria or apraxia had reduced intelligibility (significant effect size: 0.318). Low intelligibility was significantly associated with across-the-board reductions in phonemic and phonetic accuracy and with inappropriate prosody and voice. Findings are interpreted as support for motor speech disorders in adolescents with DS as explanatory constructs for their reduced intelligibility. Pending cross-validation of findings in diverse samples of persons with DS, studies are needed to assess the efficacy of motor speech classification status to guide selection of treatment methods and intelligibility targets.

Indexed as

AdolescentChildDown SyndromeFemaleHumansLanguage Development DisordersMaleRisk FactorsSpeech DisordersSpeech IntelligibilityApraxiaassessmentclassificationdysarthriaspeech motor delay

Identifiers

PMID31221010
PMCPMC6604063
OpenAlexW2952786352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.