Evidence map›Paper›PMID 31220954›Full record

ArticleInternational journal of immunopathology and pharmacology

Skullcapflavone I protects cardiomyocytes from hypoxia-caused injury through up-regulation of lincRNA-ROR.

Zhenxiao Zhang, Hui Li, Mingyang Liu, Jianshuai He, Xiaotian Zhang, Yuehua Chen

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in International journal of immunopathology and pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. CLEC3B protects H9c2 cardiomyocytes from apoptosis caused by hypoxia via the PI3K/Akt pathway.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhenxiao Zhang1 Department of Emergency, The Affiliated Hospital of Qingdao University, Qingdao, China.
Hui Li1 Department of Emergency, The Affiliated Hospital of Qingdao University, Qingdao, China.
Mingyang Liu1 Department of Emergency, The Affiliated Hospital of Qingdao University, Qingdao, China.
Jianshuai He2 Department of Anesthesiology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xiaotian Zhang2 Department of Anesthesiology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yuehua Chen3 Department of Intensive Care Unit, The Affiliated Hospital of Qingdao University, Qingdao, China.ORCID https://orcid.org/0000-0002-4646-4017
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction (MI) is a serious heart disease in which cardiomyocytes are damaged, caused by hypoxia. This study explored the possible protective activity of Skullcapflavone I (SF I), a flavonoid isolated from the root of

Indexed as

RNA, Long NoncodingAnimalsApoptosisCardiotonic AgentsCell HypoxiaCell LineFlavonesMitogen-Activated Protein KinasesMyocytes, CardiacRats, WistarUp-RegulationCardiotonic AgentsFlavonesMitogen-Activated Protein KinasesRNA, Long Noncodingskullcapflavone IflavonoidslincRNA-RORMEK/ERK pathwaymyocardial infarctionSkullcapflavone I

Identifiers

PMID31220954
PMCPMC6589964
OpenAlexW2953175433

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.