Evidence map›Paper›PMID 31220398›Full record

ReviewJournal of thrombosis and haemostasis : JTH2019

Predicting the risk of recurrent venous thrombosis: What the future might bring.

Willem M Lijfering, Jasmijn F Timp, Suzanne C Cannegieter

Abstract readReview
In one paragraph

Review in Journal of thrombosis and haemostasis : JTH, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Willem M LijferingDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Jasmijn F TimpDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Suzanne C CannegieterDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An important clinical problem in the management of venous thrombosis is to determine whether a patient can safely cease anticoagulant therapy. In this Forum article, we summarize the predictive performance of several prediction models for recurrent thrombosis, as well as for bleeding while using anticoagulants. Patients with provoked first thrombosis (considered "low risk") are now denied long-term treatment, although a strong gradient in risk can be found in this group. We furthermore discuss the problem of an unclear definition of "(un)provoked" and show that this affects the yield of currently available prediction scores plus the limitations of a "one-size-fits-all" strategy. Better prediction tools are urgently needed. We propose a strategy for future studies for which the following should be considered: (a) reporting of absolute risks next to C-statistics, (b) model applicable to all patients, (c) no discontinuation of anticoagulation for measurement of predictors.

Indexed as

Age FactorsAnticoagulantsArea Under CurveClinical Trials as TopicComorbidityForecastingHemorrhageHormone Replacement TherapyHumansNeoplasmsObesityPractice Guidelines as TopicPrognosisRecurrenceRiskROC CurveAnticoagulantsepidemiologyexpert testimonyprognosisrisksecondary preventionvenous thrombosis

Identifiers

PMID31220398
PMCPMC6851778

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.