ArticleCerebral cortex (New York, N.Y. : 1991)2020
Orchestration of Hippocampal Information Encoding by the Piriform Cortex.
Article in Cerebral cortex (New York, N.Y. : 1991), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- An Olfactory Piriform Cortex-Lateral Hypothalamus Neural Circuit Contributes to Linalool-Induced Analgesia.CNS neuroscience & therapeutics · 2026Article
- Causal relationships between somatic movement, brain structures, and mental well-being: A multi-stage Mendelian randomization study.Psychological medicine · 2026Article
- Piriform seizures mediated by the piriform-entorhino-dentate circuit induce brain-wide functional reorganization in mice.PLoS biology · 2026Article
- The role of the caudate nucleus in taste function: a comprehensive narrative review.Frontiers in neuroscience · 2026Review
- Hippocampal sequences represent working memory and implicit timing.Cell reports · 2025Article
- MRI evidence of gray matter loss in COVID-19 patients with cognitive and olfactory disorders.Annals of clinical and translational neurology · 2024Article
- Olfactory stimulation with multiple odorants prevents stress-induced cognitive and psychological alterations.Brain communications · 2024Article
- The BDNF mimetic R-13 attenuates TBI pathogenesis using TrkB-related pathways and bioenergetics.Biochimica et biophysica acta. Molecular basis of disease · 2023Article
- RGS14 expression in CA2 hippocampus, amygdala, and basal ganglia: Implications for human brain physiology and disease.Hippocampus · 2023Review
- Aging differentially affects LTCC function in hippocampal CA1 and piriform cortex pyramidal neurons.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Butanol Extract of Tinospora cordifolia Alleviates Acute Sleep Deprivation-Induced Impairments in Cognitive Functions and Neuromuscular Coordination in Middle-Aged Female Rats.Neuromolecular medicine · 2022Article
- LRP4 is required for the olfactory association task in the piriform cortex.Cell & bioscience · 2022Article
- Olfactory Evaluation in Alzheimer's Disease Model Mice.Brain sciences · 2022Review
- Olfactory Information Storage Engages Subcortical and Cortical Brain Regions That Support Valence Determination.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- RGS14 modulates locomotor behavior and ERK signaling induced by environmental novelty and cocaine within discrete limbic structures.Psychopharmacology · 2021Article
- Integrating pheromonal and spatial information in the amygdalo-hippocampal network.Nature communications · 2021Article
- Cell Proliferation in the Piriform Cortex of Rats with Motor Cortex Ablation Treated with Growth Hormone and Rehabilitation.International journal of molecular sciences · 2021Article
- Bidirectional Regulation of Hippocampal Synaptic Plasticity and Modulation of Cumulative Spatial Memory by Dopamine D2-Like Receptors.Frontiers in behavioral neuroscience · 2021Article
- Odour-Evoked Memory in Dogs: Do Odours Help to Retrieve Memories of Food Location?Animals : an open access journal from MDPI · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hippocampus utilizes olfactospatial information to encode sensory experience by means of synaptic plasticity. Odor exposure is also a potent impetus for hippocampus-dependent memory retrieval. Here, we explored to what extent the piriform cortex directly impacts upon hippocampal information processing and storage. In behaving rats, test-pulse stimulation of the anterior piriform cortex (aPC) evoked field potentials in the dentate gyrus (DG). Patterned stimulation of the aPC triggered both long-term potentiation (LTP > 24 h) and short-term depression (STD), in a frequency-dependent manner. Dual stimulation of the aPC and perforant path demonstrated subordination of the aPC response, which was nonetheless completely distinct in profile to perforant path-induced DG plasticity. Correspondingly, patterned aPC stimulation resulted in somatic immediate early gene expression in the DG that did not overlap with responses elicited by perforant path stimulation. Our results support that the piriform cortex engages in specific control of hippocampal information processing and encoding. This process may underlie the unique role of olfactory cues in information encoding and retrieval of hippocampus-dependent associative memories.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.