ArticlePloS one2019
Etiology, characteristics, and outcomes of community-onset necrotizing fasciitis in Korea: A multicenter study.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 31 citations in OpenAlex.
- Risk factors and predictors of in-hospital mortality in necrotizing fasciitis: a five-year retrospective cohort study from a tertiary care center in Colombia.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Severe necrotizing soft tissue infections (SENSEI) study: Protocol for a multi-centered audit.JPRAS open · 2026Article
- The Usefulness and Limitations of Radiologic Findings for Diagnosis of Infectious Diseases: A Call for Antimicrobial Stewardship.Infection & chemotherapy · 2025Review
- Article
- Diabetes Mellitus and Infectious Diseases: Current Evidence and Clinical Implications.Diabetes & metabolism journal · 2025Review
- Epidemiology and prognostic factors of necrotizing fasciitis in resource-limited regions based on 119 cases.Scientific reports · 2025Article
- Incidence of Bacteriobilia and the Correlation with Antibioticoprophylaxis in Low-Risk Patients Submitted to Elective Videolaparoscopic Cholecystectomy: A Randomized Clinical Trial.Antibiotics (Basel, Switzerland) · 2023Article
- Clinical Impact ofAntibiotics (Basel, Switzerland) · 2023Review
- Autologous Cell Harvesting System as Adjunct for Soft-tissue Reconstruction of Necrotizing Soft Tissue Infection.Plastic and reconstructive surgery. Global open · 2022Article
- Case Report: Necrotizing fasciitis caused byFrontiers in genetics · 2022Article
- Necrotizing Skin and Soft Tissue Infections Admitted to Intensive Care Unit in Reunion Island: A Retrospective Cohort Study.The American journal of tropical medicine and hygiene · 2021Article
- Necrotizing Soft Tissue Infection: A Single-Center Retrospective Study of Treatment and Outcomes.Cureus · 2021Article
- Klebsiella pneumoniae necrotizing fasciitis on the upper lip in a patient with uncontrolled diabetes.Archives of craniofacial surgery · 2020Article
- Common traps/pitfalls and emergency diagnosis in dermatopathology.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020Review
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Authors and funding
15 authors at 9 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNecrotizing fasciitis (NF) is a serious skin and soft tissue infection causing high mortality. Investigating region specific epidemiologic factors associated with NF is important for establishing appropriate treatment strategies. This multicenter study was done to provide an update of the microbial etiology, clinical characteristics, and outcomes of NF in Korea. MATERIALS AND
methodsA retrospective cohort of adult patients with NF was established using patient data from 13 general hospitals between January 2012 and December 2015 in Korea. We evaluated microbial etiology and clinical characteristics to identify risk factors associated with in-hospital mortality; analyses were performed using binary logistic regression models.
resultsA total of 161 patients with NF were included. The most common underlying disease was diabetes mellitus (66 cases, 41.0%). A total of 148 organisms were isolated from 119 (73.9%) patients. Enteric Gram-negative organisms (36 patients) were the most common pathogen, followed by Staphylococcus aureus (30 patients) and streptococci (28 patients). Methicillin-resistant Staphylococcus aureus (MRSA) was identified in 6.2% (10/161) of patients. Of 37 enteric Gram-negative isolates tested, 26 (70.3%) isolates were susceptible to ceftriaxone. The in-hospital mortality rate was 22.4%. Intensive care unit admission, septic shock, and Gram-negative organism infections were significantly associated with in-hospital mortality, and surgery was not a favorable prognostic factor.
conclusionsAs initial empirical antibiotics, glycopeptides against MRSA and broad-spectrum antibiotics against third-generation cephalosporin-resistant organisms should be considered for patients with community-onset NF in Korea.
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