ArticlemSystems2019
A "Cultural" Renaissance: Genomics Breathes New Life into an Old Craft.
Article in mSystems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed.
- Genome-based predictions of metabolic preferences and substrate phenotypes in psychrotrophic bacteria from permafrost environments.Microbiology spectrum · 2026Article
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- Discovery and cultivation of prokaryotic taxa in the age of metagenomics and artificial intelligence.The ISME journal · 2025Article
- Microbial single-cell applications under anoxic conditions.Applied and environmental microbiology · 2024Review
- Microbial consortium assembly and functional analysis via isotope labelling and single-cell manipulation of polycyclic aromatic hydrocarbon degraders.The ISME journal · 2024Article
- Article
- Review
- Cultivation of marine bacteria of the SAR202 clade.Nature communications · 2023Article
- Utilization of-Omic technologies in cold climate hydrocarbon bioremediation: a text-mining approach.Frontiers in microbiology · 2023Review
- Review
- Site and land-use associations of soil bacteria and fungi define core and indicative taxa.FEMS microbiology ecology · 2022Article
- Heme auxotrophy in abundant aquatic microbial lineages.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Portable and Rapid Sequencing Device with Microbial Community-Guided Culture Strategies for Precious Field and Environmental Samples.mSystems · 2021Article
- Methodological Approaches Frame Insights into Endophyte Richness and Community Composition.Microbial ecology · 2021Article
- Cultivating the Bacterial Microbiota ofmSystems · 2021Article
- Strategies for culturing active/dormant marine microbes.Marine life science & technology · 2021Review
- Viable but nonculturable bacteria and their resuscitation: implications for cultivating uncultured marine microorganisms.Marine life science & technology · 2021Review
- Innovations to culturing the uncultured microbial majority.Nature reviews. Microbiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sometimes, to move ahead, you must take a look at where you have been. Culturing microbes is a foundational underpinning of microbiology. Before genome sequencing, researchers spent countless hours tediously deducing the nutritional requirements of bacterial isolates and tinkering with medium formulations to entice new microbes into culture. This art of cultivation took a back seat to the powerful molecular tools of the last 25 years, and as a result, many researchers have forgotten the utility of having a culture in hand. This perception is changing, as there is clearly a renewed interest in isolating microbes from various environments. Here, I suggest three focus areas to ensure continued growth and success of this "cultural" renaissance, including (i) setting clear cultivation goals, (ii) funding exploratory cultivation, and (iii) culturing and studying unusual organisms. "Unculturable" is a frame of mind, not a state of microbiology; it is time to dust off the bottle of yeast extract.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.